For other salt forms or a guaranteed higher purity please inquire. In pppApG a 5'-ATP unit is connected with a 5'-GMP unit via a 3' → 5' linkage to form a linear dinucleotide. pppApG is a potential endogenous metabolite of the metazoan second messenger 2',3'-cGAMP (c[G(2',5')pA(3',5')p], Cat. No. C 161) and/or of the bacterial signalling nucleotide 3'3'-cGAMP (c-(ApGp), Cat. No. C 117). Kranzusch et al. (2014) reported pppApG to be the linear dinucleotide intermediate in the enzymatic production of 3',3'-cGAMP by the Vibrio cholerae pathogenicity factor DncV. References: Kranzusch, P.J. et al., Cell, 158, 1011 - 1021 (2014); Deng, T. et al., J. Virol., 80, 2337 - 2348 (2006).
| Cat. No. | T 050 |
| CAS number | [68892-47-7] |
| Purity | > 95% HPLC |
| Salt form | Sodium |
| Appearance | 10 mM aqueous solution |
| Storage temperature | -70°C / -94°F |
| Molecular formula | C₂₀H₂₈N₁₀O₂₀P₄ (free acid) |
| Molecular weight [g/mol] | 852.4 (free acid) |
| Absorption max [nm] | 256 |
| Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] | 25050 |
| UV pH value | 7 |
| Solvent for UV data | Water |
