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Alternative structural projections:


8- (6- [Fluoresceinyl]aminohexylthio)- ß- phenyl- 1, N²- ethenoguanosine- 3', 5'- cyclic monophosphate ( 8-Fluo-AHT-PET-cGMP )
Fluorescent PKG agonist
Cat. No.: F 013
CAS No.: [pending]
Shipping: ambient

For other salt forms please inquire. Fluorescent activator of cyclic GMP-dependent protein kinase (λexc 494 nm, λem 517 nm), but most probably inhibitor of the retinal type cGMP-gated ion channel, thus suitable for distinction between kinase and ion channel mediated effects. Resistant against mammalian cyclic nucleotide-dependent phosphodiesterases.

The category "Future Products" lists structures that are already "in the pipeline" and nearly ready to be offered as regular products. Please just inquire, your interest will certainly accelerate the process.

Cat. No. F 013
CAS number [pending]
Purity > 95%
Salt form Sodium
Appearance Solid
Storage temperature -20°C / -4°F
Light-sensitive Yes
Molecular formula C₄₅H₃₈N₆O₁₃PS · Na
Molecular weight [g/mol] 956.9
Modifications 1-cGMP, 2-cGMP, 8-cGMP
Target PKG (cGK) Activator
Excitation max [nm] 494
Emission max [nm] 517
Absorption max [nm] 499
Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] 79000
UV pH value 9
Solvent for UV data Water