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TNP-β-L-GTP

Guanine- 2', 3'- O- (2, 4, 6- trinitrophenyl)- β- L- ribofuranosyl- 5'- O- triphosphate ( TNP-β-L-GTP )
Fluorescent analogue of β-L-GTP
Cat. No.: G 035
    
CAS No.: [pending]
Shipping: Dry ice
Product Name Price (net) Qty
Cat. No.: G 035-01
Unit: 1 µmol / ~0.7 mg
$165.00

For other salt forms please inquire. Fluorescent analogue of β-L-GTP, the mirror image version of naturally occurring β-D-GTP, where the guanine nucleobase is connected to β-L-ribose. TNP fluorophore with λexc 408 nm and λem 552 nm. It is sensitive to indicators of local environment such as polarity and viscosity, and frequently exhibits a spectral shift and fluorescence enhancement upon binding to a protein. Potential inhibitor of various adenylyl cyclase isoforms and soluble guanylyl cyclase (sGC). References for the related TNP-GTP: Hiratsuka, T., J. Biol. Chem., 260, 4784 - 4790 (1985); Suryanarayana et al., J. Pharmacol. Exp. Ther., 330, 687 - 695 (2009).

 

Vial containing 1 ml of 1 mM aqueous solution of pH 8.

Cat. No. G 035
CAS number [pending]
Purity > 95% HPLC
Salt form Sodium
Appearance 10 mM aqueous solution
Storage temperature -70°C / -94°F
Light-sensitive Yes
Molecular formula C₁₆H₁₇N₈O₂₀P₃ (free acid)
Molecular weight [g/mol] 734.3 (free acid)
Excitation max [nm] 408
Emission max [nm] 552
Absorption max [nm] 408
Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] 26500
UV pH value 8
Solvent for UV data Water