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6- (β- D- 2- Deoxyribofuranosyl)- 3, 4- dihydro- 8H- pyrimido- [4, 5- c]- [1, 2]- oxazin- 7- one- 5'- O- (1- thiotriphosphate), Sp- isomer ( 2'-Deoxy-P-nucleoside-5'-O-(1-thiotriphosphate), Sp-isomer / Sp-dPTP-α-S )
Cat. No.: D 106
CAS No.: [627502-68-5]
Shipping: Dry ice

For other salt forms or a guaranteed higher purity please inquire. Triphosphate analogue with artificial base for directed mutagenesis experiments. Increased metabolic stability compared to dPTP (Cat. No. D 114). Accepted by DNA polymerase for incorporation of phosphorothioate into DNA.Reference for the parent nucleotide dPTP: Zaccolo et al., J. Mol. Biol., 255, 589 - 603 (1996); Wong et al., Biotechnol. J., 3, 74 - 83 (2008). Vial containing 100 µl of 10 mM aqueous solution of pH 7.6.


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Cat. No. D 106
CAS number [627502-68-5]
Purity >95% HPLC
Salt form Sodium
Appearance 10 mM aqueous solution
Storage temperature -70°C / -94°F
Molecular formula C₁₁H₁₈N₃O₁₃P₃S (free acid)
Molecular weight [g/mol] 525.3 (free acid)
Absorption max [nm] 294
Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] 6700
UV pH value 7
Solvent for UV data Water