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Sp-dPTP-α-S

6- (β- D- 2- Deoxyribofuranosyl)- 3, 4- dihydro- 8H- pyrimido- [4, 5- c]- [1, 2]- oxazin- 7- one- 5'- O- (1- thiotriphosphate), Sp- isomer ( 2'-Deoxy-P-nucleoside-5'-O-(1-thiotriphosphate), Sp-isomer / Sp-dPTP-α-S )
Cat. No.: D 106
    
CAS No.: [pending]
Shipping: Dry ice

For other salt forms or a guaranteed higher purity please inquire. Triphosphate analogue with artificial base for directed mutagenesis experiments. Increased metabolic stability compared to dPTP (Cat. No. D 114). Accepted by DNA polymerase for incorporation of phosphorothioate into DNA.Reference for the parent nucleotide dPTP: Zaccolo et al., J. Mol. Biol., 255, 589 - 603 (1996); Wong et al., Biotechnol. J., 3, 74 - 83 (2008). Vial containing 100 µl of 10 mM aqueous solution of pH 7.6.

 


The category "Future Products" lists structures that are already "in the pipeline" and nearly ready to be offered as regular products. Please just inquire, your interest will certainly accelerate the process.

Cat. No. D 106
CAS number [pending]
Purity >95% HPLC
Salt form Sodium
Appearance 10 mM aqueous solution
Storage temperature -70°C / -94°F
Molecular formula C₁₁H₁₈N₃O₁₃P₃S (free acid)
Molecular weight [g/mol] 525.3 (free acid)
Absorption max [nm] 294
Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] 6700
UV pH value 7
Solvent for UV data Water