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  1. Target: PKA (cAK) Inhibitor
cAMP modified at the exocyclic oxygen
  1. equatorial (Rp-) (9)
Modifications
  1. 2-cAMP (1)
  2. 8-cAMP (6)
Lipophilicity

Lipophilicity ranking is based on log kw data. To be membrane-permeant, analogues should have a log kw of at least 1.2
See also: Lipophilic Ranking of Cyclic Nucleotide Analogs

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PDE- resistant PKA Inhibitors

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