Specially purified from adenosine, cAMP and Sp-cAMPS. For other salt forms please inquire. Competitive inhibitor of protein kinase A type I and II (cyclic AMP antagonist). Prefers type II of protein kinase A. Resistant against mammalian cyclic nucleotide-dependent phosphodiesterases. Significantly more lipophilic compared to cAMP. Detailed technical information and updated reference list available on request. Rp-cAMPS is also available in an inexpensive lower purity form (A 002 T Economy Grade) and as bulk ware. Ref.: Gjertsen et al., J. Biol. Chem., 270, 20599 - 20607 (1995).
Cat. No. | A 002 S |
CAS number | [73208-40-9] |
Purity | > 99% HPLC |
Salt form | Sodium |
Storage temperature | -20°C / -4°F |
Molecular formula | C₁₀H₁₁N₅O₅PS · Na |
Molecular weight [g/mol] | 367.3 |
cAMP modified at the exocyclic oxygen | equatorial (Rp-) |
Target | PKA (cAK) Inhibitor |
Lipophilicity | 1.21 |
Absorption max [nm] | 259 |
Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] | 15200 |