Alternative structural projections:
Phosphodiesterase-resistant ligand for affinity chromatography of cAMP and cGMP binding proteins and suitable for modification with fluorophores and other markers. Detailed technical information available. This ligand is also available with a longer spacer (Sp-2-AHA-cAMPS; Cat. No. A 068) and already coupled to agarose (Sp-2-AEA-cAMPS-Agarose; Cat. No. A 087).
References for a similar product (Sp-8-AEA-cAMPS: Hanke et al., N. Biotechnol. 2011 Jul; 28(4):294-301. doi: 10.1016/j.nbt.2010.12.001. Epub 2010 Dec 13; Chepurny et al., Mol. Endocrinol., 27, 1267 - 1282 (2013).
| Cat. No. | A 093 |
| CAS number | [pending] |
| Purity | > 98% HPLC |
| Salt form | Free acid |
| Appearance | Solid |
| Storage temperature | -20°C / -4°F |
| Molecular formula | C₁₂H₁₈N₇O₅PS |
| Molecular weight [g/mol] | 403.4 |
| cAMP modified at the exocyclic oxygen | axial (Sp-) |
| Modifications | 2-cAMP |
| Target | PKA (cAK) Activator |
| Lipophilicity | 1.06 |
| Absorption max [nm] | 258 |
| Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] | 12600 |
| UV pH value | 7 |
| Solvent for UV data | Water |
