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7-MCM-caged 8-pCPT-2'-O-Me-cAMP

(7- Methoxycoumarin- 4- yl)methyl- 8- (4- chlorophenylthio)- 2'- O- methyladenosine- 3', 5'- cyclic monophosphate ( 7-MCM-caged 8-pCPT-2'-O-Me-cAMP )
Prodrug of the EPAC agonist 8-pCPT-2'-O-Me-cAMP
Cat. No.: M 107
    
CAS No.: [pending]
Shipping: ambient

For other salt forms please inquire.  Mixture of isomers. 7-MCM-caged 8-pCPT-2'-O-Me-cAMP is an only weakly fluorescent, caged precursor of a cAMP-based second messenger analogue, which upon irradiation, releases both, the EPAC activator 8-pCPT-2'-O-Me-cAMP (Cat. No. C 041) and a fluorescent coumarin analogue. Reference for a related product: Hagen et al., Angew. Chem. Int. Ed., 40, 1046 - 1048 (2001).

 


The category "Future Products" lists structures that are already "in the pipeline" and nearly ready to be offered as regular products. Please just inquire, your interest will certainly accelerate the process.

Cat. No. M 107
Patent Information The reagent is protected under patent EP 1511757 and foreign equivalents issued or licensed to BIOLOG Life Science Institute.
CAS number [pending]
Purity >98% HPLC
Salt form Sodium
Appearance Solid
Storage temperature -20°C / -4°F
Light-sensitive Yes
Molecular formula C₂₈H₂₅ClN₅O₉PS (free acid)
Molecular weight [g/mol] 674.0 (free acid)
Modifications 8-cAMP, 2'-cAMP
Target Epac Activator
Excitation max [nm] ~322
Emission max [nm] ~381
UV pH value 7
Solvent for UV data Water