Membrane-permeant precursor of the PKA activator 8-Cl-cAMP (Cat. No. C 007). Metabolic activation by esterases releases the polar active analogue, which is trapped inside the cell. Detailed technical information available. Reference: J. Kruppa, Ph.D. thesis, University of Bremen, Germany, 1996. Biolog also offers Phosphate tris(acetoxymethyl)ester (PO4-AM3, Cat. No. P 030) which is recommended as control reagent in nucleotide-AM ester applications.
Cat. No. | C 050 |
CAS number | [pending] |
Purity | > 97% HPLC for mixture of isomers |
Storage temperature | -20°C / -4°F |
Molecular formula | C₁₃H₁₅ClN₅O₈P |
Molecular weight [g/mol] | 435.7 |
Modifications | 8-cAMP |
Target | PKA (cAK) Activator |
Absorption max [nm] | 262 |
Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] | 17000 |