For other salt forms please inquire. Cyclic AMP connected to the relatively small Pharos 575 dye (λexc 577 nm, λem 605-617 nm) by a spacer. The fluorophore can be excited e.g. by a Kr/Ar laser. Due to its high lipophilicity and bright red fluorescence 8-[φ-575]-cAMP is especially suitable for studies with intact cells. Upon binding to PKA a small hypsochromic shift is observed. Detailed technical information available. References: Moll et al., BMC Biochem., 9: 18 (2008); Agarwal et al., Sci. Rep., 6:19577 (2016).
Cat. No. | P 019 |
CAS number | [pending] |
Purity | > 98% HPLC |
Salt form | Sodium |
Storage temperature | -20°C / -4°F |
Light-sensitive | True |
Modifications | 8-cAMP |
Target | PKA (cAK) Activator |
Excitation max [nm] | 577 |
Emission max [nm] | 605 - 617 |
Lipophilicity | 3.07 |
Absorption max [nm] | 575 |
Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] | 20960 |