Highly membrane-permeant precursor of the second messenger cyclic AMP. Mixture of axial and equatorial isomer.
Hydrolysis slowly releases the polar cAMP which is trapped inside the cell and subsequently metabolized, resulting in an elevated cAMP level for a prolonged period. Detailed technical information and updated reference list available. Reference: Engels et al., J. Med. Chem., 20, 907 - 911 (1977).
Cat. No. | A 065 |
CAS number | [62742-71-6] |
Purity | > 95% HPLC for mixture of axial and equatorial isomer |
Storage temperature | -20°C / -4°F |
Molecular formula | C₁₇H₁₈N₅O₆P |
Molecular weight [g/mol] | 419.3 |
Target | PKA (cAK) Activator |
Absorption max [nm] | 259 |
Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] | 15000 |