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Cyclic (uridine- (2' −> 5')- monophosphate- adenosine- (3' −> 5')- monophosphate) ( c[U(2',5')pA(3',5')p] / 2'3'-cUAMP / 2',5'-3',5'-cUAMP ), sodium salt

Hybrid purine-pyrimidine cyclic dinucleotide
Cat. No.: C 399
CAS No.: [pending]
Shipping: ambient
Product Name Price (net) Qty
Cat. No.: C 399-005
Unit: 0.5 µmol / ~318 µg

For other salt forms or analogues please inquire. c[U(2',5')pA(3',5')p] is a hybrid purine-pyrimidine cyclic dinucleotide that was identified as a natural nucleotide second messenger in the oyster species Crassostrea gigas (C. gigas, Pacific oyster) and Crassostrea virginica (C. virginica, Eastern oyster). In C. virginica, c[U(2',5')pA(3',5')p] induced a gene expression pattern strongly associated with innate immunity, including upregulated expression of genes encoding transcription factors (NF-kB, IRFs, and STATs), immune receptors (NLRs, RLRs, cGLRs, and STING), and proteins with homology to human interleukins and inhibitor of apoptosis (IAP) factors. Reference: Li et al.,Cell (2023), https://doi.org/10.1016/j.cell.2023.05.038.



Cat. No. C 399
CAS number [pending]
Purity > 95% HPLC
Salt form Sodium
Storage temperature -20°C / -4°F
Molecular formula C₁₉H₂₃N₇O₁₄P₂ (free acid)
Molecular weight [g/mol] 635.4 (free acid)
Absorption max [nm] 260
Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] 22500
UV pH value 7
Solvent for UV data Water