For other salt forms please inquire. Cyclic oligoadenylates were found to be novel bacterial second messengers involved in the Type III CRISPR-Cas-associated detection and degradation of invasive genetic elements in many prokaryotes. The Streptococcus thermophilus type III-A CRISPR-Cas system produces c-pentaAMP as well as a range of differently sized cyclic oligoadenylates both in vitro and in vivo, although only the least abundant c-hexaAMP (Biolog Cat. No. C 332) activated the Csm6 ribonuclease of this organism. Reference: Smalakyte et al., Nucleic Acids Res., 48, 9204 - 9217 (2020).
| Cat. No. | C 394 |
| CAS number | [163499-42-1] |
| Purity | > 95% HPLC |
| Salt form | Sodium |
| Appearance | Crystallized or lyophilized solid |
| Storage temperature | -20°C / -4°F |
| Molecular formula | C₅₀H₆₀N₂₅O₃₀P₅ (for free acid) |
| Molecular weight [g/mol] | 1646.0 (for free acid) |
| Absorption max [nm] | 258 |
| Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] | 67500 |
| UV pH value | 7 |
