For other salt forms please inquire. Biotinylated analogue of the metazoan cyclic dinucleotide second messenger c[G(2',5')pA(3',5')p] (
aka cGAMP(2'-5') or 2'3'-cGAMP,
Cat. No. C 161) in which the biotin label is attached to position 8 of the guanine nucleobase via a 11 atom spacer. Potential tracer in immunoassays, for affinity chromatography or pull-down assays. c[G(2',5')pA(3',5')p] was found to be the metazoan second messenger produced by the mammalian innate immune DNA sensor cGAMP synthase (cGAS). Detailed technical information available. References for c[G(2',5')pA(3',5')p]: Gao et al.,
Cell,
153, 1094 - 1107 (2013); Ablasser et al.,
Nature,
498, 380- 384 (2013); Zhang et al.,
Mol. Cell,
51, 226 - 235 (2013) Diner et al.,
Cell Rep.,
3, 1355 - 1361 (2013)