For other salt forms please inquire. Sulfur-modified analogue of the bacterial second messenger c-diGMP (Cat. No. C 057) with increased metabolic stability. Rp,Rp-c-diGMPSS can be useful in studies on ligand-receptor interactions. Detailed technical information available. References: Yan et al., Bioorg. Med. Chem. Lett., 18, 5631 - 5634 (2008); Shanahan et al., J. Am. Chem. Soc., 133, 15578 - 15592 (2011); Shanahan et al., Biochemistry, 52, 365 - 377 (2013).
| Cat. No. | C 129 |
| CAS number | [1259875-41-6] |
| Purity | > 95% HPLC |
| Salt form | Sodium |
| Storage temperature | -20°C / -4°F |
| Molecular formula | C₂₀H₂₄N₁₀O₁₂P₂S₂ (free acid) |
| Molecular weight [g/mol] | 722.6 (free acid) |
| Absorption max [nm] | 253 |
| Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] | 26100 |
- 1. Shanahan C. A., Gaffney B. L., Jones R. A.Strobel S. A., Biochemistry, 52, 365 - 377 (2013), "Identification of c-di-GMP Derivatives Resistant to an EAL Domain Phosphodiesterase"
- 2. Shanahan C. A., Gaffney B. L., Jones R. A.Strobel S. A., J. Am. Chem. Soc., 133, 15578 - 15592 (2011), "Differential Analogue Binding by Two Classes of C-Di-GMP Riboswitches"
- 3. Yan H., Wang X., KuoLee R.Chen W., Bioorg. Med. Chem. Lett., 18, 5631 - 5634 (2008), "Synthesis and Immunostimulatory Properties of the Phosphorothioate Analogues of c-di-GMP"
