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Cyclic (adenosine monophosphate- 8- bromoguanosine monophosphate) ( c-(Ap-8-Br-Gp) ), sodium salt
Mono-functionalized analogue of c-(ApGp) / cGAMP
Cat. No.: C 145
CAS No.: [pending]
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Cat. No.: C 145-001
Unit: 0.1 µmol / ~75 µg
For other salt forms please inquire. Halogenated analogue of the potential bacterial second messenger c-(ApGp) (aka cGAMP, Cat. No. C 117) which is useful for binding studies and as precursor for further modifications with spacers or labels. c-(ApGp) is considered to play a role in Vibrio cholerae pathogenesis and was also reported to stimulate the production of interferon via STING. Detailed technical information available. References for c-(ApGp): Davies et al., Cell, 149, 358 - 370 (2012); Wu et al., Science, 339, 826 - 830 (2013).
Cat. No. C 145
CAS number [pending]
Purity > 95% HPLC
Salt form Sodium
Storage temperature -20°C / -4°F
Molecular formula C₂₀H₂₃BrN₁₀O₁₃P₂ (free acid)
Molecular weight [g/mol] 753.3 (free acid)
Absorption max [nm] 262
Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] 27800