Alternative structural projections:
For other salt forms please inquire. Potentially membrane permeant, fluorescent analogue of the metazoan cyclic dinucleotide second messenger and STING activator c[G(2',5')pA(3',5')p] (aka cGAMP(2'-5') or 2'3'-cGAMP, Cat. No. C 161), where both, the 2'- and the 3'-hydroxyl group at the ribose moieties, are esterified by the fluorescent MANT group. The fluorophore (λexc 355 nm; λem 448 nm) has a certain sensitivity for its environment and can change its spectral properties upon binding. Compare: Hiratsuka, Biochim. Biophys. Acta, 742, 496 - 503 (1983). Detailed technical information available.
| Cat. No. | C 284 |
| CAS number | [pending] |
| Purity | >93% HPLC |
| Salt form | Sodium |
| Appearance | Solid |
| Storage temperature | -20°C / -4°F |
| Light-sensitive | Yes |
| Molecular formula | C₃₆H₃₈N₁₂O₁₅P₂ (for free acid) |
| Molecular weight [g/mol] | 940.7 (for free acid) |
| Excitation max [nm] | 355 |
| Emission max [nm] | 448 |
| Absorption max [nm] | 255 |
| Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] | 38950 |
| UV pH value | 8 |
| Solvent for UV data | Water |
