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Alternative structural projections:

c[3'-MANT-G(2',5')p-2'-MANT-A(3',5')p] / Di-MANT-2'3'-cGAMP

Cyclic (3'- O- (N'- methylanthraniloyl)guanosine- (2' −> 5')- monophosphate- 2'- O- (N'- methylanthraniloyl)adenosine- (3' −> 5')- monophosphate) ( c[3'-MANT-G(2',5')p-2'-MANT-A(3',5')p] / Di-MANT-2'3'-cGAMP ), sodium salt
Fluorescent analogue of the metazoan second messenger 2'3'-cGAMP
Cat. No.: C 284
    
CAS No.: [pending]
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Product Name Price (net) Qty
Cat. No.: C 284-001
Unit: 0.1 µmol / ~94 µg
$235.00

For other salt forms please inquire. Potentially membrane permeant, fluorescent analogue of the metazoan cyclic dinucleotide second messenger and STING activator c[G(2',5')pA(3',5')p] (aka cGAMP(2'-5') or 2'3'-cGAMP, Cat. No. C 161), where both, the 2'- and the 3'-hydroxyl group at the ribose moieties, are esterified by the fluorescent MANT group. The fluorophore (λexc 355 nm; λem 448 nm) has a certain sensitivity for its environment and can change its spectral properties upon binding. Compare: Hiratsuka, Biochim. Biophys. Acta, 742, 496 - 503 (1983). Detailed technical information available.

Cat. No. C 284
CAS number [pending]
Purity >93% HPLC
Salt form Sodium
Appearance Solid
Storage temperature -20°C / -4°F
Light-sensitive Yes
Molecular formula C₃₆H₃₈N₁₂O₁₅P₂ (for free acid)
Molecular weight [g/mol] 940.7 (for free acid)
Excitation max [nm] 355
Emission max [nm] 448
Absorption max [nm] 255
Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] 38950
UV pH value 8
Solvent for UV data Water