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Br-ANT-ITP

2'- / 3'- O- (5- Bromoanthraniloyl)inosine- 5'- O- triphosphate ( Br-ANT-ITP ), sodium salt

Fluorescent ITP analogue
Cat. No.: B 118
    
CAS No.: [1350521-52-6]
Shipping: Dry ice
Product Name Price (net) Qty
Cat. No.: B 118-05
Unit: 5 µmol / ~3.5 mg
$290.00

For other salt forms or a guaranteed higher purity please inquire. Analogue of inosine-5'-triphosphate with only moderate intrinsic fluorescence (λexc 345 nm, λem ~427 nm). The fluorophore has a certain sensitivity for its environment and is supposed to change its spectral properties upon binding. Useful for research into purine triphosphate-dependent receptor proteins. Potent inhibitor of various adenylyl cyclase isoforms and soluble guanylyl cyclase (sGC). References: Dove et al., Mol. Pharmacol., 85, 598 - 607 (2014), Geduhn et al., J. Pharmacol. Exp. Ther., 336, 104 - 115 (2011)

 

Vial containing 100 µl of 10 mM aqueous solution of pH 7.6.

Cat. No. B 118
CAS number [1350521-52-6]
Purity > 95% HPLC
Salt form Sodium
Appearance 10 mM aqueous solution
Storage temperature -70°C / -94°F
Light-sensitive Yes
Molecular formula C₁₇H₁₉BrN₅O₁₅P₃ (for free acid)
Molecular weight [g/mol] 706.2 (for free acid)
Excitation max [nm] 345
Emission max [nm] 427
Absorption max [nm] 248
Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] 15000
UV pH value 7
Solvent for UV data Water