ANT-GTP is an analogue of guanosine-5'-triphosphate, where either the ribose 2' or the 3' hydroxyl group has been modified wtih the relatively small fluorescent anthraniloyl group (λexc 330 nm, λem ~428nm). The ANT fluorophore has a certain sensitivity for its environment and can change its spectral properties upon binding. Inhibitor of various adenylyl cyclase isoforms. Detailed technical information available. References: Pinto et al., Biochem. Phamacol, 82, 358 - 370 (2011); Hiratsuka, Biochim. Biophys. Acta, 742, 496 - 503 (1983).
Vial containing 100 µl of 10 mM aqueous solution of pH 7.6.
| Cat. No. | A 214 |
| CAS number | [pending] |
| Purity | > 95% HPLC |
| Salt form | Tetrasodium |
| Appearance | Aqueous solution |
| Storage temperature | -70°C / -94°F |
| Light-sensitive | Yes |
| Molecular formula | C₁₇H₂₁N₆O₁₅P₃ (free acid) |
| Molecular weight [g/mol] | 642.31 (free acid) |
| Absorption max [nm] | 249 |
| Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] | 20700 |
| UV pH value | 8 |
| Solvent for UV data | Water |
