For other salt forms please inquire. Hydrolytically stable analogue of ADP and starting structure for synthesis of α/β hydrolysis-resistant tri- and polyphosphates. Inhibitor of CD73. Detailed technical information available. References: Hoehn et al., J. Neurochem., 54, 256 - 265 (1990); Synnestvedt et al., J. Clin. Invest., 110, 993 - 1002 (2002).
Vial containing 500 µl of 10 mM aqueous solution of pH 7.6
| Cat. No. | A 070 |
| CAS number | [104835-70-3] |
| Purity | > 95% HPLC |
| Salt form | sodium salt |
| Appearance | 10 mM aqueous solution of pH 7.6 |
| Storage temperature | -70°C / -94°F |
| Molecular formula | C₁₁H₁₇N₅O₉P₂ (free acid) |
| Molecular weight [g/mol] | 425.2 (free acid) |
| Absorption max [nm] | 259 |
| Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] | 15000 |
- 1. Song E.-K., Park H.-J., Kim J.-S., Lee H.-H., Kim U.-H.Han M.-K., J. Biochem. Biophys. Methods, 63, 161 - 169 (2005), "A Novel Fluorometric Assay for ADP-ribose Pyrophosphatase Activity"
- 2. Synnestvedt K., Furuta G. T., Comerford K. M., Louis N., Karhausen J., Eltzschig H. K., Hansen K. R., Thompson L. F.Colgan S. P., J. Clin. Invest., 110, 993 - 1002 (2002), "Ecto-5'-Nucleotidase (CD73) Regulation by Hypoxia-Inducible Factor-1 Mediates Permeability Changes in Intestinal Epithelia"
- 3. Picher M., Sevigny J., D'Orleans-Juste P.Beaudoin A. R., Biochem. Pharmacol., 51, 1453 - 1460 (1996), "Hydrolysis of P2-Purinoreceptor Agonists by a Purified Ectonucleotidase from the Bovine Aorta, the ATP-Diphosphohydrolase"
- 4. Hoehn K.White T. D., J. Neurochem., 54, 256 - 265 (1990), "Role of Excitatory Amino Acid Receptors in K+- and Glutamate-Evoked Release of Endogenous Adenosine from Rat Cortical Slices"
