Fluorescent analogue of adenine (λexc 300 nm, λem 410 nm) and potential biomarker of lipid peroxidation. Detailed technical information available. References: Holt et al., Carcinogenesis, 19, 1763 - 1769 (1998); Chen & Chang., Chem. Res. Toxicol., 17, 963 - 971 (2004).
| Cat. No. | E 012 |
| CAS number | [13875-63-3] |
| Purity | > 95% HPLC |
| Storage temperature | -20°C / -4°F |
| Light-sensitive | True |
| Molecular formula | C₇H₅N₅ |
| Molecular weight [g/mol] | 159.2 |
| Excitation max [nm] | 300 |
| Emission max [nm] | 410 |
| Absorption max [nm] | 268 |
| Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] | 9850 |
| UV pH value | 6.5 |
- 1. Chen H. J.Chang C. M., Chem. Res. Toxicol., 17, 963 - 971 (2004), "Quantification of Urinary Excretion of 1,N6-Ethenoadenine, a Potential Biomarker of Lipid Peroxidation, in Humans by Stable Isotope Dilution Liquid Chromatography-Electrospray Ionization-Tandem Mass Spectrometry: Comparison with Gas Chromatography-Mass Spectrometry"
- 2. Holt S., Yen T. Y., Sangaiah R.Swenberg J. A., Carcinogenesis, 19, 1763 - 1769 (1998), "Detection of 1,N6-Ethenoadenine in Rat Urine after Chloroethylene Oxide Exposure"
- 3. Dutta S. P., Mittelman A.Chheda G. B., Biochem. Med., 23, 179 - 184 (1980), "Metabolism of 1,N6-Ethenoadenosine"
