For other salt forms or metabolites please inquire. Site-selective cyclic AMP analogue with high selectivity for site A of protein kinase A type I and for site B of type II. Acts synergistically together with analogues having opposite site selectivity. Combination with e.g.
2-Cl-8-HA-cAMP (Cat. No. C 071) preferentially activates type I, while e.g. with
6-MBC-cAMP (Cat. No. M 012) selects type II. Increased metabolic stability and membrane permeability compared to cAMP. Detailed technical information and updated references available. Reference: Skalhegg et al.,
J. Biol. Chem.,
267, 15707 - 15714 (1992).