The nitrated derivative of cGMP, 8-NO2-cGMP (8-Nitro-cGMP), is considered to play an important role in NO-mediated signal transduction. Formation of protein Cys-cGMP adducts by 8-NO2-cGMP was identified as a new post-translational modification of proteins, which is called S-guanylation. Reference: Sawa et al., Nat. Chem. Biol., 3, 727 - 735 (2007).
| Cat. No. | N 011 |
| CAS number | [913645-39-3] |
| Purity | > 98% HPLC |
| Salt form | Sodium |
| Storage temperature | -20°C / -4°F |
| Light-sensitive | True |
| Molecular formula | C₁₀H₁₀N₆O₉P · Na |
| Molecular weight [g/mol] | 412.2 |
| Modifications | 8-cGMP |
| Target | PKG (cGK) Activator |
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