Several potential metabolites of the anti cancer drug candidate 8-Cl-cAMP (Cat. No. C 007) are offered by BIOLOG as references for metabolic monitoring: While 8-Cl-5'-AMP, 8-Cl-5’-ADP, 8-Cl-5’-ATP, 8-Cl-adenosine, 8-Cl-2'-deoxyadenosine, 8-chloroinosine, 8-chloroadenine, 8-chloroxanthine and 8-Cl-cAMP itself are listed as regular products under their corresponding categories, 8-Cl-5'-IMP and 8-chlorohypoxanthine are available upon request. For 8-chloroxanthosine and 8-chloroxanthosine-5'-O-monophosphate please inquire.
| Cat. No. | C 008 |
| CAS number | [pending] |
| Molecular weight [g/mol] | 458.6 |
- 1. Dennison J. B., Ayres M., Kaluarachchi K., Plunkett W.Gandhi V., J. Biol. Chem., 285, 8022 - 8030 (2010), "Intracellular Succinylation of 8-Chloroadenosine and its Effect on Fumarate Levels"
- 2. Han Z., Chatterjee D.Wyche J. H., J. Pharmacol. Exp. Ther., 265, 790 - 794 (1992), "Proliferation of Nontransformed Cells is Inhibited by Adenosine Metabolite of But Not by Parental 8-Cl-Cyclic AMP"
- 3. Van Lookeren Campagne M. M., Diaz F. V., Jastorff B.Kessin R. H., Cancer Res., 51, 1600 - 1605 (1991), "8-Chloroadenosine 3',5'-Monophosphate Inhibits the Growth of Chinese Hamster Ovary and Molt-4 Cells Through its Adenosine Metabolite"
