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Alternative structural projections:


8- (6- Aminohexylamino)adenosine- 3', 5'- cyclic monophosphate; immobilized on agarose gel ( 8-AHA-cAMP-Agarose )
cyclic AMP immobilized on agarose gel 
Cat. No.: A 028
CAS No.: [pending]
Shipping: ambient
Product Name Price (net) Qty
Cat. No.: A 028-06
Unit: 0.6 ml
Cat. No.: A 028-25
Unit: 2.5 ml
Cat. No.: A 028-60
Unit: 6 ml

The second messenger cyclic AMP immobilized on agarose by an aminohexylamino spacer attached to position 8 of the ligand. The gel can be used for affinity chromatography of various cyclic nucleotide-responsive proteins such as protein kinases, phosphodiesterases and others. This ligand is also offered with a shorter spacer (8-AEA-cAMP-Agarose, Cat. No. A 020) and as PDE-resistant version (Sp-8-AHA-cAMPS-Agarose, Cat. No. A 013). Detailed technical information available. References: Dills et al., Biochemistry, 15, 3724 - 3731 (1976); Margarucci et al., Mol. BioSyst. 7, 2311 - 2319 (2011).  Normally all affinity gels are supplied in pre-packed columns. The free beads without a column are available upon request.


Appearance: Suspension in 30 mM Na2HPO4 buffer (pH 7).

Cat. No. A 028
CAS number [pending]
Appearance Suspension in 30 mM Na₂HPO₄ buffer (pH 7)
Storage temperature 4°C / 39°F
Modifications 8-cAMP
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  • 2. Margarucci L., Roest M., Preisinger C., Bleijerveld O. B., van Holten T. C., Heck A. J. R.Scholten A., Mol. Biosyst., 7, 2311 - 2319 (2011), "Collagen Stimulation of Platelets Induces a Rapid Spatial Response of cAMP and cGMP Signaling Scaffolds"
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  • 10. Erneux C., Miot F., Van Haastert P. J. M.Jastorff B., J. Cyclic Nucleotide Protein Phosphorylation Res., 10, 463 - 472 (1985), "The Binding of Cyclic Nucleotide Analogs to a Purified Cyclic GMP- Stimulated Phosphodiesterase from Bovine Adrenal Tissue"
  • 11. O'Brian C. A., Roczniak S. O., Bramson H. N., Baraniak J., Stec W. J.Kaiser E. T., Biochemistry, 21, 4371 - 4376 (1982), "A Kinetic Study of Interactions of (Rp)- and (Sp)-Adenosine Cyclic 3',5'-Phosphorothioates with Type II Bovine Cardiac Muscle Adenosine Cyclic 3',5'-Phosphate Dependent Protein Kinase"
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