Alternative structural projections:
Site selective cAMP analogue with preference for site B of R I of cAMP-dependent protein kinase. In combination with 8-PIP-cAMP (Cat. No. P 002), which selects site A of R I and site B of R II specific synergistic activation of kinase type I can be obtained. Reference: Skalhegg et al., J. Biol. Chem., 267, 15707 - 15714 (1992). Also suitable as a ligand in affinity chromatography (8-AHA-cAMP-Agarose; Cat. No. A 028) or surface plasmon resonance chip technology (Herberg et al., J. Mol. Biol., 298, 329 - 339 (2000); Moll et al., J. Neural. Transm., 113, 1015 - 1032 (2006)) and for modification with fluorophores. Detailed technical information and selected references available.
| Cat. No. | A 011 |
| CAS number | [39824-30-1] |
| Purity | > 98% HPLC |
| Salt form | Free acid |
| Storage temperature | -20°C / -4°F |
| Molecular formula | C₁₆H₂₆N₇O₆P |
| Molecular weight [g/mol] | 443.4 |
| Modifications | 8-cAMP |
| Target | PKA (cAK) Activator |
| Lipophilicity | 1.34 |
| Absorption max [nm] | 273 |
| Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] | 17000 |
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