Alternative structural projections:
The second messenger cyclic GMP immobilized on agarose by an aminoethylthio spacer attached to position 8 of the ligand. The gel can be used for affinity chromatography of various cyclic nucleotide-responsive proteins such as protein kinases, phosphodiesterases and others. This type of gel is offered as PDE-resistant version (Sp-8-AET-cGMPS-Agarose, Cat. No. A 010) as well. Detailed technical information available. References: Schlossmann et al., Nature, 404, 197 - 201 (2000); Scholten et al., J. Proteome Res., 5, 1435 - 1447 (2006); Antl et al., Blood, 109, 552 - 559 (2007); Margarucci et al., Mol. BioSyst., 7, 2311 - 2319 (2011).
Normally all affinity gels are supplied in pre-packed columns. The free beads without a column are available upon request.
Appearance: Suspension in 30 mM Na2HPO4 buffer (pH 7).
| Cat. No. | A 019 |
| CAS number | [pending] |
| Appearance | Suspension in 30 mM Na₂HPO₄ buffer (pH 7) |
| Storage temperature | 4°C / 39°F |
| Modifications | 8-cGMP |
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