The second messenger cyclic AMP immobilized on agarose by an aminoethylamino spacer attached to position 8 of the ligand. The gel can be used for affinity chromatography of various cyclic nucleotide-responsive proteins such as protein kinases, phosphodiesterases and others. This ligand is also offered with a longer spacer (8-AHA-cAMP-Agarose, Cat. No. A 028) and as a PDE-resistant version (Sp-8-AEA-cAMPS-Agarose, Cat. No. A 008). Detailed technical information available. References: Dills et al., Biochemistry, 15, 3724 - 3730 (1976); Scholten et al., J. Proteome Res., 5, 1435 - 1447 (2006).
Normally all affinity gels are supplied in pre-packed columns. The free beads without a column are available upon request.
|Cat. No.||A 020|