Alternative structural projections:
For other salt forms or higher purity please inquire.
Biotinylated analogue of β-NAD+, representing a non-radioactive alternative to radio-labelled β-NAD+ for corresponding studies. Detailed technical information available. Reference for a structurally related 6-Biotin-17-NAD+: Zhang & Snyder, Biochemistry, 32, 2228 - 2233 (1993); Bakondi et al., J. Histochem. Cytochem., 50, 91 - 98 (2002); Klebl et al., Arch. Biochem. Biophys., 347, 155 - 162 (1997).
Biotinylated analogue of β-NAD+, representing a non-radioactive alternative to radio-labelled β-NAD+ for corresponding studies. Detailed technical information available. Reference for a structurally related 6-Biotin-17-NAD+: Zhang & Snyder, Biochemistry, 32, 2228 - 2233 (1993); Bakondi et al., J. Histochem. Cytochem., 50, 91 - 98 (2002); Klebl et al., Arch. Biochem. Biophys., 347, 155 - 162 (1997).
| Cat. No. | N 012 |
| CAS number | [1369508-04-2] |
| Purity | > 95% HPLC |
| Salt form | Sodium |
| Storage temperature | -70°C / -94°F |
| Molecular formula | C₄₅H₆₈N₁₂O₁₈P₂S (free acid) |
| Molecular weight [g/mol] | 1,159.1 (free acid) |
| Absorption max [nm] | 265 |
| Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] | 22000 |
- 1. Bakondi E., Bai P., Szabo E., Hunyadi J., Gergely P., Szabo C.Virag L., J. Histochem. Cytochem., 50, 91 - 98 (2002), "Detection of Poly(ADP-Ribose) Polymerase Activation in Oxidatively Stressed Cells and Tissues Using Biotinylated NAD Substrate"
- 2. Cheung A.Zhang J., Analytical Biochemistry, 282, 24 - 28 (2000), "A Scintillation Proximity Assay for Poly(ADP-Ribose) Polymerase"
- 3. Klebl B. M., Göpel S. O.Pette D., Arch. Biochem. Biophys., 347, 155 - 162 (1997), "Specificity and Target Proteins of Arginine-Specific Mono-ADP-Ribosylation in T-Tubules of Rabbit Skeletal Muscle"
- 4. Zhang J.Snyder S. H., Biochemistry, 21, 2228 - 2233 (1993), "Purification of a Nitric Oxide-Stimulated ADP-Ribosylated Protein Using Biotinylated Beta-Nicotinamide Adenine Dinucleotide"
