Collaborative Papers and Posters
| 111 |
Almahariq, M.; Tsalkova, T.; Mei, F.C.; Chen, H.; Zhou, J.; Sastry, S.K.; Schwede, F.; Cheng, X., Mol. Pharmacol., 83, 122 - 128 (2013): "A Novel EPAC Specific Inhibitor Suppresses Pancreatic Cancer Cell Migration and Invasion" |
| 110 |
Düvel, J.; Bertinetti, D.; Möller, S.; Schwede, F.; Morr, M.; Wissing, J.; Radamm, L.; Zimmermann, B.; Genieser, H.-G.; Jänsch, L.; Herberg, F.W.; Häussler, S., J. Microbiol. Methods., 88, 229 - 236 (2012): "A Chemical Proteomics Approach to Identify c-di-GMP Binding Proteins in Pseudomonas Aeruginosa" |
| 109 |
Kusch, J.; Thon, S.; Schulz, E.; Biskup, C.; Nache, V.; Zimmer, T.; Seifert, R.; Schwede, F.; Benndorf, K., Nat. Chem. Biol., 8, 162 - 169 (2012): "How Subunits Cooperate in cAMP-induced Activation of Homotetrameric HCN2 Channels" |
| 108 |
Jäger, R.; Russwurm, C.; Schwede, F.; Genieser, H.-G.; Koesling, D.; Russwurm, M., J. Biol. Chem., 287, 1210 - 1219 (2012): "Activation of PDE10 and PDE11 Phosphodiesterases" |
| 107 |
Hammerschmidt, A.; Chatterji, B.; Zeiser, J.; Schröder, A.; Genieser, H.-G.; Pich, A.; Kaever, V.; Schwede, F.; Wolter, S.; Seifert, R., PLoS ONE, 7, 39848 (2012): "Binding of Regulatory Subunits of cyclic AMP-dependent Protein Kinase to cyclic CMP Agarose" |
| 106 |
Nache, V.; Zimmer, T.; Wongsamitkul, N.; Schmauder, R.; Kusch, J.; Reinhardt, L.; Bönigk, W.; Seifert, R.; Biskup, C.; Schwede, F.; Benndorf, K., Sci. Signal., 5 (2012): "Differential Regulation by Cyclic Nucleotides of the CNGA4 and CNGB1b Subunits in Olfactory Cyclic Nucleotide-Gated Channels" |
| 105 |
Huseby, S.; Gausdal, G.; Keen, T.J.; Kjærland, E.; Krakstad, C.; Myhren, L.; Brønstad, K.; Kunick, C.; Schwede, F.; Genieser, H.-G.; Kleppe, R.; Doeskeland, S.O., Cell Death Dis. published online 2011 December 8. doi: 10.1038/cddis.2011.124 (2011): "Cyclic AMP induces IPC leukemia cell apoptosis via CRE-and CDK-dependent Bim transcription" |
| 104 |
Börner, S.; Schwede, F.; Schlipp, A.; Berisha, F.; Calebiro, D.; Lohse, M.J.; Nikolaev, V.O., Nat. Protoc., 6, 427 - 438 (2011): "FRET Measurements of Intracellular cAMP Concentrations and cAMP Analog Permeability in Intact Cells" |
| 103 |
Hanke, S.E.; Bertinetti, D.; Badel, A.; Schweinsberg, S.; Genieser, H.-G.; Herberg, F.W., N. Biotechnol., 28, 294 - 301 (2011): "Cyclic Nucleotides as Affinity Tools: Phosphorothioate cAMP Analogues Adress Specific PKA Subproteomes" |
| 102 |
Dzhura, I.; Chepurny, O.G.; Leech, C.A.; Roe, M.W.; Dzhura, E.; Xu, X.; Lu, Y.; Schwede, F.; Genieser, H.-G.; Smrcka, A.V.; Holz, G.G., Islets, 3, 121 - 128 (2011): "Phospholipase C-epsilon Links Epac2 Activation to the Potentiation of Glucose-stimulated Insulin Secretion from Mouse Islets of Langerhans" |
| 101 |
Werner, K.; Schwede, F.; Genieser, H.-G.; Geiger, J.; Butt, E., Naunyn Schmiedebergs Arch. Pharmacol., 384, 169 - 176 (2011): "Quantification of cAMP and cGMP Analogs in Intact Cells: Pitfalls in Enzyme Immunoassays for Cyclic Nucleotides" |
| 100 |
Holz, G.G.; Chepurny, O.G.; Leech, C.A.; Dzhura, I.; Kelley, G.G.; Roe, W.R.; Dzhura, E.; Li, X.; Schwede, F.; Genieser, H.-G., Biophys. J., 98, 680 - 680 (2010): "A Permissive Role for Protein Kinase A in Support of Epac Agonist-Stimulated Human Islet Insulin Secretion" |
| 99 |
Leech, C.A.; Dzhura, I.; Chepurny, O.G.; Schwede, F.; Genieser, H.-G.; Holz, G.G., Islets, 2, 72 - 81 (2010): "Facilitation of beta-cell KATP Channel Sulfonylurea Sensivity by a cAMP Analog Selective for the cAMP-regulated Guanine Nucleotide Exchange Factor Epac" |
| 98 |
Chepurny, O.G.; Kelley, G.G.; Dzhura, I.; Leech, C.A.; Roe, M.W.; Dzhura, E.; Li, X.; Schwede, F.; Genieser, H.-G.; Holz, G.G., Am. J. Physiol.-Endocrinol. Metabol., 298, 622 - 633 (2010): "PKA-dependent Potentiation of Glucose-stimulated Insulin Secretion by Epac Activator 8-pCPT-2'-O-Me-cAMP-AM in Human Islets of Langerhans" |
| 97 |
Béres, T.; Zatloukal, M.; Voller, J.; Niemann, P.; Gahsche, M.C.; Tarkowski, P.; Novák, O.; Hanus, J.; Strnad, M.; Dolezal, K., Anal. Bioanal. Chem., 398, 2071 - 2080 (2010): "Tandem Mass Spectrometry Identification and LC-MS Quantification of Intact Cytokinin Nucleotides in K-562 Human Leukemia Cells" |
| 96 |
Voller, J.; Zatloukal, M.; Lenobel, R.; Dolezal, K.; Béres, T.; Krystof, V.; Spíchal, L.; Niemann, P.; Dzubák, P.; Hajdúch, M.; Strnad, M., Phytochem., 71, 1350 - 1359 (2010): "Anticancer Activity of Natural Cytokinins: A Structure-activity Relationsship Study" |
| 95 |
Jäger, R.; Schwede, F.; Genieser, H.-G.; Koesling, D.; Russwurm, M., Br. J. Pharmacol., 161, 1645 - 1660 (2010): "Activation of PDE2 and PDE5 cy Specific GAF Ligands: Delayed Activation of PDE5" |
| 94 |
Kusch, J.; Biskup, C.; Thon, S.; Schulz, E.; Nache, V.; Zimmer, T.; Schwede, F.; Benndorf, K., Neuron, 67, 75 - 85 (2010): "Interdependence of Receptor Activation and Ligand Binding in HCN2 Pacemaker Channels" |
| 93 |
Erikstein, B.S.; McCormack, E.; Tronstad, K.J.; Schwede, F.; Berge, R.; Gjertsen, B.T., Leuk Res., 34, 77 - 84 (2010): "Protein Kinase A Activators and the Pan-PPAR Agonist Tetradecylthioacetic Acid Elicit Synergistic Anti-leukaemic Effects in AML through CREB" |
| 92 |
Bertinetti, D.; Schweinsberg, S.; Hanke, S.E.; Schwede, F.; Bertinetti, O.; Drewianka, S.; Genieser, H.-G.; Herberg, F.W., BMC Chem Biol, 9 (2009): "Chemical tools selectively target components of the PKA system" |
| 91 |
Chepurny, O.G.; Leech, C.A.; Kelley, G.G.; Dzhura, I.; Dzhura, E.; Li, X.; Rindler, M.J.; Schwede, F.; Genieser, H.-G.; Holz, G.G., J. Biol. Chem., 284, 10728 - 10736 (2009): "Enhanced Rap1 activation and insulin secretagogue properties of an acetoxymethyl ester of an Epac-selective cyclic AMP analog in rat INS-1 cells: Studies with 8-pCPT-2'-O-Me-cAMP-AM." |
| 90 |
Kelley, G.G.; Chepurny, O.G.; Schwede, F.; Genieser, H.-G.; Leech, C.A.; Roe, M.W.; Li, X.; Dzhura, I.; Dzhura, E.; Afshari, P.; Holz, G.G., Islets, 1, 260 - 265 (2009): "Glucose-dependent Potentation of Mouse Islet Insulin Secretion by Epac Activator 8-pCPT-2'-O-Me-cAMP-AM" |
| 89 |
Herfindal, L.; Kasprzykowski, F.; Schwede, F.; Lankiewicz, L.; Fladmark, K.E.; Lukomska, J.; Wahlsten, M.; Sivonen, K.; Grzonka, Z.; Jastorff, B.; Doeskeland, S.O., J. Med. Chem., 52, 5758 - 5762 (2009): "Acyloxymethyl Esterification of Nodularin-R and Microcystin-LA Produces Inactive Protoxins That Become Reactivated and Produce Apoptosis Inside Intact Cells" |
| 88 |
Poppe, H.; Rybalkin, S.D.; Rehmann, H.; Hinds, T.R.; Tang, X.-B.; Christensen, A.E.; Schwede, F.; Genieser, H.-G.; Bos, J.L.; Doeskeland, S.O.; Beavo, J.A.; Butt, E., Nature Methods, 5, 277 - 278 (2008): "Cyclic Nucleotide Analogs as Probes of Signaling Pathways" |
| 87 |
Holz, G.G.; Chepurny, O.G.; Schwede, F., Cell. Signal., 20, 10 - 20 (2008): "Epac-selective cAMP Analogs: New Tools with which to Evaluate the Signal Transduction Properties of cAMP-regulated Guanine Nucleotide Exchange Factors" |
| 86 |
Schweinsberg, S.; Moll, D.; Burghardt, N.C.; Hahnefeld, C.; Schwede, F.; Zimmermann, B.; Drewianka, S.; Werner, L.; Kleinjung, F.; Genieser, H.-G.; Schuchhardt, J.; Herberg, F.W., Proteomics, 8, 1212 - 1220 (2008): "Systematic interpretation of cyclic nucleotide binding studies using KinetXBase" |
| 85 |
Moll, D.; Prinz, A.; Brendel, C.M.; Berrera, M.; Guske, K.; Zaccolo, M.; Genieser, H.-G.; Herberg, F.W., BMC Biochem., 9, 18 - 18 (2008): "Biochemical Characterization and Cellular Imaging of a Novel, Membrane Permeable Fluorescent cAMP Analog" |
| 84 |
Vliem, M.J.; Ponsioen, B.; Schwede, F.; Pannekoek, W.-J.; Riedl, J.; Kooistra, M.R.H.; Jalink, K.; Genieser, H.-G.; Bos, J.L.; Rehmann, H., ChemBioChem, 9, 2052 - 2054 (2008): "8-pCPT-2'-O-Me-cAMP-AM: An Improved Epac-selective cAMP Analogue" |
| 83 |
Rehmann, H.; Arias-Palomo, E.; Hadders, M.A.; Schwede, F.; Llorca, O.; Bos, J.L., Nature, 455, 124 - 127 (2008): "Structure of Epac2 in Complex with a cyclic AMP Analogue and RAP1B" |
| 82 |
Ouyang, M.; Zhang, L.; Zhu, J.J.; Schwede, F.; Thomas, S.A., PNAS, 105, 11993 - 11997 (2008): "Epac Signaling is Required for Hippocampus-dependent Memory Retrieval" |
| 81 |
Rodriguez-Collazo, P.; Snyder, S.K.; Chiffer, R.C.; Bressler, E.A.; Voss, T.C.; Anderson, E.P.; Genieser, H.-G.; Smith, C.L., Exp. Cell Res., 314, 2855 - 2869 (2008): "cAMP Signaling Regulates Histone H3 Phosphorylation and Mitotic Entry Through a Disruption of G2 Progression" |
| 80 |
Biskup, C.; Kusch, J.; Schulz, E.; Nache, V.; Schwede, F.; Lehmann, F.; Hagen, V.; Benndorf, K., Nature, 446, 440 - 443 (2007): "Relating ligand binding to activation gating in CNGA2 channels" |
| 79 |
Laxman, S.; Riechers, A.; Sadilek, M.; Schwede, F.; Beavo, J.A., PNAS, 103, 19194 - 19199 (2006): "Hydrolysis Products of cAMP Analogs Cause Transformation of Trypanosoma Brucei from Slender to Stumpy-like Forms" |
| 78 |
Bryn, T.; Mahic, M.; Enserink, J.M.; Schwede, F.; Aandahl, E.M.; Tasken, K., J. Immunol., 176, 7361 - 7370 (2006): "The cyclic AMP-Epac1-Rap1 Pathway is Dissociated from Regulation of Effector Functions in Monocytes but Acquires Immunoregulatory Function in Mature Macrophages" |
| 77 |
Dao, K.K.; Teigen, K.; Kopperud, R.K.; Hodneland, E.; Schwede, F.; Christensen, A.E.; Martinez, A.; Doeskeland, S.O., J. Biol. Chem., 281, 21500 - 21511 (2006): "Epac1 and cAMP-dependent Protein Kinase Holoenzyme Have Similar cAMP Affinity, but Their cAMP Domains Have Distinct Structural Features and Cyclic Nucleotide Recognition" |
| 76 |
Kang, G.; Chepurny, O.G.; Malester, B.; Rindler, M.J.; Rehmann, H.; Bos, J.L.; Schwede, F.; Coetzee, W.A.; Holz, G.G., J. Physiol.-London, 573, 595 - 609 (2006): "cAMP Sensor Epac as a Determinant of ATP-sensitive Potassium Channel Activity in Human Pancreatic Beta Cells and Rat INS-1 Cells" |
| 75 |
Makarevich, A.V.; Sirotkin, A.V.; Genieser, H.-G., Anim. Reprod. Sci., 81, 125 - 136 (2004): "Action of Protein Kinase A Regulators on Secretory Activity of Porcine Granulosa Cells in Vitro" |
| 74 |
Mahic, M.; Bryn, T.; Enserink, J.M.; Schwede, F.; Aandahl, E.M.; Tasken, K., Poster #THP019 Montreal, 12 (2004): "Modulation of Monocyte Activation by Cyclic AMP is Mainly Mediated Through Protein Kinase A" |
| 73 |
Selheim, F.; Krakstad, C.; Christensen, A.-E.; Hagland, H.; Schwede, F.; Genieser, H.-G.; Doeskeland, S.O., Poster # THP017 Montreal, 12 (2004): "The cAMP Receptor Epac Has a Permissive Role for cAMP-dependent Protein Kinase Action to Protect PC-12 Pheochromocytoma Cells Against Stress-induced Apoptosis and Induce Neuronal Differentiation" |
| 72 |
Genieser, H.-G.; Bos, J.L.; Christensen, A.E.; Doeskeland, S.O.; Havemann, U.; Manzau, U.; Rehmann, H.; Schwede, F., Poster #THP016 Montreal, 12 (2004): "Analogues of Cyclic AMP to Distinguish Between PKA and Epac" |
| 71 |
Weissinger, E.M.; Oettrich, K.; Evans, C.; Genieser, H.-G.; Schwede, F.; Dangers, M.; Dammann, E.; Kolb, H.-J.; Mischak, H.; Ganser, A.; Kolch, W., Brit. J. Cancer, 91, 186 - 192 (2004): "Activation of Protein Kinase A (PKA) by 8-Cl-cAMP as a Novel Approach for Antileukaemic Therapy" |
| 70 |
Kang, G.; Joseph, J.W.; Chepurny, O.G.; Monaco, M.; Wheeler, M.B.; Bos, J.L.; Schwede, F.; Genieser, H.-G.; Holz, G.G., J. Biol. Chem., 278, 8279 - 8285 (2003): "Epac-Selective cAMP Analog 8-pCPT-2'-O-Me-cAMP As A Stimulus For Ca 2+ -Induced Ca 2+ Release And Exocytosis In Pancreatic Beta-Cells" |
| 69 |
Rangarajan, S.; Enserink, J.M.; Kuiperij, H.B.; de Rooij, J.; Price, L.S.; Schwede, F.; Bos, J.L., J. Cell Biol., 160, 487 - 493 (2003): "Cyclic AMP Induces Integrin-mediated Cell Adhesion Through Epac and Rap1 Upon Stimulation of the ß2-Adrenergic Receptor" |
| 68 |
Rehmann, H.; Schwede, F.; Doeskeland, S.O.; Wittinghofer, A.; Bos, J.L., J. Biol. Chem., 278, 38548 - 38556 (2003): "Ligand-mediated Activation of the cAMP-responsive Guanine Nucleotide Exchange Factor Epac" |
| 67 |
Bartsch, M.; Zorn-Kruppa, M.; Kühl, N.; Genieser, H.-G.; Schwede, F.; Jastorff, B., Biol. Chem., 384, 1321 - 1326 (2003): "Bioactivatable, Membrane-permeant Analogs of Cyclic Nucleotides as Biological Tools for Growth Control of C6 Glioma Cells" |
| 66 |
Christensen, A.E.; Selheim, F.; de Rooij, J.; Dremier, S.; Schwede, F.; Dao, K.K.; Martinez, A.; Maenhaut, C.; Bos, J.L.; Genieser, H.-G.; Doeskeland, S.O., J. Biol. Chem., 278, 35394 - 35402 (2003): "cAMP Analog Mapping of Epac1 and cAMP-Kinase. Discriminating Analogs Demonstrate that Epac and cAMP-Kinase Act Synergistically to Promote PC-12 Cell Neurite Extension" |
| 65 |
Christensen, A.E.; de Rooij, J.; Kopperud, R.K.; Nilsen, O.K.; Dao, K.K.; Schwede, F.; Bos, J.L.; Genieser, H.-G.; Doeskeland, S.O., Abstract of the 13th Protein Kinase Symposium, 5 - 5 (2002): "Comparison of the cAMP Binding Sites of EPAC-1 and cAMP-Kinase" |
| 64 |
Enserink, J.M.; Christensen, A.E.; de Rooij, J.; van Triest, M.; Schwede, F.; Genieser, H.-G.; Doeskeland, S.O.; Blank, J.L.; Bos, J.L., Nature Cell Biol., 4, 901 - 906 (2002): "A Novel Epac-specific cAMP Analogue Demonstrates Independent Regulation of Rap 1 and ERK" |
| 63 |
Sirotkin, A.V.; Makarevich, A.V.; Pivko, J.; Genieser, H.-G., Asian Austral. J. Anim. Sci., 15, 1045 - 1050 (2002): "Intracellular Mechanisms of Growth Hormone Action on Apoptosis in Cultured Porcine Ovarian Granulosa Cells" |
| 62 |
Sirotkin, A.V.; Makarevich, A.V.; Kwon, H.B.; Kotwica, J.; Genieser, H.-G.; Pivko, J., Endocrine Abstracts, 4, 79 (2002): "Effect of Growth Hormone on Porcine Ovarian Cells and its Intracellular Mechanisms" |
| 61 |
Maronde, E.; Korf, H.W.; Niemann, P.; Genieser, H.-G., J. Pineal Res., 31, 183 - 185 (2001): "Direct Comparison of the Potency of Three Novel cAMP Analogs to Induce CREB-Phosphorylation in Rat Pinealocytes" |
| 60 |
Wätjen, W.; Benters, J.; Haase, H.; Schwede, F.; Jastorff, B.; Beyersmann, D., Toxicol., 157, 167 - 175 (2001): "Zn2+ and Cd2+ Increase the cyclic GMP level in PC12 Cells by Inhibition of the cyclic Nucleotide Phosphodiesterase" |
| 59 |
Schwede, F.; Christensen, A.; Liauw, S.; Hippe, T.; Kopperud, R.K.; Jastorff, B.; Doeskeland, S.O., Biochemistry, 39, 8803 - 8812 (2000): "8-Substituted cAMP Analogues Reveal Marked Differences in Adaptability, Hydrogen Bonding, and Charge Accomodation between Homologous Binding Sites (AI/AII and BI/BII) in cAMP Kinase I and II" |
| 58 |
Sirotkin, A.V.; Mertin, D.; Süvegova, K.; Makarevich, A.V.; Genieser, H.-G.; Luck, M.R.; Osadchuk, L.V., Gen. Comp. Endocrinol., 117, 207 - 217 (2000): "Effect of Restricted Food Intake on Production, Catabolism, and Effects of IGF-I and Cyclic Nucleotides in Cultured Ovarian Tissue of Domestic Nutria (Myocastor coypus)" |
| 57 |
Schwede, F.; Brustugun, O.T.; Zorn-Kruppa, M.; Doeskeland, S.O.; Jastorff, B., Bioorg. Med. Chem. Lett., 10, 571 - 573 (2000): "Membrane-permeant, Bioactivatable Analogues of cGMP as Inducers of Cell Death in IPC-81 Leukemia Cells" |
| 56 |
Sirotkin, A.V.; Makarevich, A.V.; Genieser, H.-G.; Kotwica, J.; Hetenyi, L., Exp. Clin. Endocrinol. Diabetes, 108, 214 - 219 (2000): "Effect of four cGMP Analogues with Different Mechanisms of Action on Hormone Release by Porcine Ovarian Granulosa Cells In Vitro" |
| 55 |
Christensen, A.; Dao, K.K.; Doeskeland, S.O.; Schwede, F.; Jastorff, B.; Genieser, H.-G.; de Rooij, J.; Bos, J.L.; Rehmann, H.; Kraemer, A.; Wittinghofer, A., 12th Protein Kinase Symp. "NO/cGMP and Protein Kinase Signaling" Bad Brückenau/Germany (2000): "8-Modified cAMP Analogs give Insight into the Geometries of the cAMP Binding Sites of RI, RII and EPAC-1" |
| 54 |
Schwede, F.; Maronde, E.; Genieser, H.-G.; Jastorff, B., Pharmacol. Ther., 87, 199 - 226 (2000): "Cyclic Nucleotide Analogs as Biochemical Tools and Prospective Drugs" |
| 53 |
Sirotkin, A.V.; Makarevich, A.V.; Pivko, J.; Kotwica, J.; Genieser, H.-G.; Bulla, J., J. Steroid Biochem. Mol. Biol., 74, 1 - 9 (2000): "Effect of cGMP Analogues and Protein Kinase G Blocker on Secretory Activity, Apoptosis and the cAMP/Protein Kinase A System in Porcine Ovarian Granulosa Cells In Vitro" |
| 52 |
Sirotkin, A.V.; Mertin, D.; Süvegova, K.; Makarevich, A.V.; Genieser, H.-G.; Osadchuk, L.V., Animal Production Review (2000): "The Cyclic Nucleotide-IGF-I System as Possible Mediator of Effect of Nutrition on Ovarian Activity in Domestic Nutria (Myocastor coypus)" |
| 51 |
Sirotkin, A.V.; Mertin, D.; Süvegova, K.; Makarevich, A.V.; Genieser, H.-G.; Luck, M.R.; Osadchuk, L.V., Scientifur, 24, 211 - 211 (2000): "Effect of Restricted Food Intake on Production, Catabolism, and Effects of IGF-I and Cyclic Nucleotides in Cultured Ovarian Tissue of Domestic Nutria (Myocastor coypus)" |
| 50 |
Maronde, E.; Wicht, H.; Tasken, K.; Genieser, H.-G.; Dehghani, F.; Olcese, J.; Korf, H.-W., J. Pineal Res., 27, 170 - 182 (1999): "CREB Phosphorylation and Melatonin Biosynthesis in the Rat Pineal Gland: Involvement of cyclic AMP-dependent Protein KinaseType II" |
| 49 |
Sirotkin, A.; Makarevic, A.; Kotwica, J.; Genieser, H.-G.; Bulla, J., J. Farm. Animal. Sci., 32, 11 - 14 (1999): "Effect of Chemical Analogues of cAMP and cGMP on Hormone and Growth Factor Secretion by Porcine Ovarian Cells" |
| 48 |
Mertin, D.; Sirotkin, A.V.; Süvegova, K.; Makarevich, A.V.; Genieser, H.-G.; Luck, M.R.; Osadchuk, L.V., Society for the Study of Fertility Aberystwyth, 32 (1999): "The Cyclic Nucleotide - IGF-I System as a Possible Link Between Nutrion and Reproduction in Domestic Nutria" |
| 47 |
Schwede, F.; Genieser, H.-G.; Jastorff, B., Cell. Mol. Biol. Lett., 4, 466 (1999): "Cyclic Nucleotide Analogs as Prospective Drugs" |
| 46 |
Sirotkin, A.; Makarevich, A.; Chribikova, J.; Genieser, H.-G.; Taradajnik, T.; Marnet, P.-G.; Chrenek, P.; Schaeffer, H.-J.; Mlyncek, M.; Kubek, A.; Bulla, J., Journal for Agricultural Sciences, 43, 391 - 398 (1999): "Secretion and Effects of Growth Factors in Farm Animal and Human Ovaries" |
| 45 |
Cho-Chung, Y.S.; Jastorff, B.; Genieser, H.-G., USA patent 5916, 843 (1998): "Cyclic AMP Analogues, Individually and in Pairs, to Inhibit Neoplastic Cell Growth" |
| 44 |
Wei, J.-Y.; Cohen, E.D.; Genieser, H.-G.; Barnstable, C.J., J. Mol. Neurosci., 10, 53 - 64 (1998): "Substituted cGMP Analogs Can Act as Selective Agonists of the Rod Photoreceptor cGMP-Gated Cation Channel" |
| 43 |
Hebert, M.C.; Schwede, F.; Jastorff, B.; Cote, R.H., J. Biol. Chem., 273, 5557 - 5565 (1998): "Structural Features of the Noncatalytic cGMP Binding Sites of Frog Photoreceptor Phoshodiesterase Using cGMP Analogs" |
| 42 |
Walton, T.J.; Bayliss, M.A.; Pereira, M.L.; Games, D.E.; Genieser, H.-G.; Brenton, A.G.; Harris, F.M.; Newton, R.P., Rapid Commun. Mass Spectrom., 12, 449 - 455 (1998): "Fast-atom Bombardment Tandem Mass Spectrometry of Cyclic Nucleotide Analogues Used as Site-selective Activators of Cyclic Nucleotide-dependent Protein Kinases" |
| 41 |
Vaandrager, A.B.; Edixhoven, M.; Bot, A.G.M.; Kroos, M.A.; Jarchau, T.; Lohmann, S.M.; Genieser, H.-G.; De Jonge, H.R., J. Biol. Chem., 272, 11816 - 11823 (1997): "Endogenous Type II cGMP-Dependent Protein Kinase Exists as a Dimer in Membranes and can be Functionally Distinguished from the Type I Isoforms" |
| 40 |
Krass, J.D.; Jastorff, B.; Genieser, H.-G., Anal. Chem., 69, 2575 - 2581 (1997): "Determination of Lipophilicity by Gradient Elution High-Performance Liquid Chromatography" |
| 39 |
Jastorff, B.; Schultz, C.; Barrett, K.E.; Schwede, F.; Kruppa, J.; Keely, S., Bioorg. Medicinal Chem. Lett., 7, 945 - 948 (1997): "Bioactivatable Derivatives of 8- Substituted cAMP- Analogues" |
| 38 |
Genieser, H.-G.; Walter, U.; Butt, E., US Patent 5625056 of April 29 (1997): "Derivatives of Cyclic Guanosine-3',5'-Monophosphorothioate" |
| 37 |
Sirotkin, A.V.; Makarevic, A.V.; Genieser, H.-G., 3rd Intl. Conf. Cyclic Nucleotide Phosphodiesterases ( From Genes to Therapies ) Scotland (1996): "The Effect of PDE Inhibitors and Other Regulators of PKA on the Secretory Activity of Porcine Ovarian Granulosa Cells" |
| 36 |
Kroner, C.; Boekhoff, I.; Lohmann, S.M.; Genieser, H.-G.; Breer, H., Eur. J. Biochem., 236, 632 - 637 (1996): "Regulation of Olfactory Signalling Via cGMP-dependent Protein Kinase" |
| 35 |
Wei, J.Y.; Cohen, E.D.; Yan, Y.-Y.; Genieser, H.-G.; Barnstable, C.J., Biochemistry, 35, 16815 - 16823 (1996): "Identification of Competitive Antagonists of the Rod Photoreceptor cGMP-Gated Cation Channel: Beta-Phenyl-1,N(2)-Etheno-Substituted cGMP Analogues as Probes of the cGMP-Binding Site" |
| 34 |
Wei, J.Y.; Cohen, E.D.; Yan, Y.-Y.; Genieser, H.-G.; Barnstable, C.J., American Society for Neuroscience, 880 (1996): "PET-substituted cGMP Analogs: Novel Antagonists of Rod Photoreceptor cGMP-gated Channel" |
| 33 |
Schwede, F., Ph.D. Thesis (1996): "Synthese und Eigenschaften ausgewählter Analoga von cGMP und ihr Einsatz in der biologischen Forschung" |
| 32 |
Sirotkin, A.V.; Makarevich, A.V.; Genieser, H.-G., J. Physiol. Pharmacol., 47, 134 (1996): "Effect of Regulators of Protein Kinase A on IGF-I and Steroid Secretion by Porcine Granulosa Cells in Vitro" |
| 31 |
Hoffmann, C.; Genieser, H.-G.; Veron, M.; Jastorff, B., Bioorg. Med. Chem. Lett., 6, 2571 - 2574 (1996): "Novel Synthesis of Nucleoside 5'-Polyphosphates" |
| 30 |
Gjertsen, B.T.; Mellgren, G.; Otten, A.; Maronde, E.; Genieser, H.-G.; Jastorff, B.; Vintermyr, O.K.; McKnight, G.S.; Doeskeland, S.O., J. Biol. Chem., 270, 20599 - 20607 (1995): "Novel (Rp)-cAMPS Analogs as Tools for Inhibition of cAMP-Kinase in Cell Culture" |
| 29 |
Ruchaud, S.; Zorn, M.; Davilar-Villar, E.; Genieser, H.-G.; Hoffmann, C.; Gjertsen, B.T.; Doeskeland, S.O.; Jastorff, B.; Lanotte, M., Cell. Pharmacol., 2, 127 - 140 (1995): "Evidence for Several Pathways of Biological Response to Hydrolysable cAMP-Analogues Using a Model System of Apoptosis in IPC-81 Leukaemia Cells" |
| 28 |
Gjertsen, B.T.; Mellgren, G.; Vintermyr, O.K.; Genieser, H.-G.; Jastorff, B.; Doeskeland, S.O., Int. Conference on Second Messenger & Phosphoproteins TN USA (1995): "The Basal cAMP-Dependent Protein Kinase (cAK) Activity in Resting Hepatocytes Can Be inhibited By Rp-8-Br-cAMPS, and Has a Permissive Role For IL-1ß Action" |
| 27 |
Butt, E.; Pöhler, D.; Genieser, H.-G.; Huggins, J.P.; Bucher, B., Br. J. Pharmacol., 116, 3110 - 3116 (1995): "Inhibition of Cyclic GMP-dependent Protein Kinase-mediated Effects by (Rp)-8-bromo-PET- cyclic GMPS" |
| 26 |
Genieser, H.-G., Proc. 9. Int. Conf. Second Mess. & Phosphoprot. TN USA (1995): "Lipophilic Ranking of Biologically Important Cyclic Nucleotides" |
| 25 |
Genieser, H.-G.; Bucher, B.; Butt, E., 9 th International Conference on Second Messenger & Phosphoproteins (1995): "Rp-8-Br-PET-cGMPS, A New Potent Inhibitor of Cyclic GMP-dependent Protein Kinase" |
| 24 |
Ruchaud, S.; Duprez, E.; Gendron, M.-C.; Houge, G.; Genieser, H.-G.; Jastorff, B.; Doeskeland, S.O.; Lanotte, M., Proc. Natl. Acad. Sci. USA, 91, 8428 - 8432 (1994): "Two Distinctly Regulated Events, Priming and Triggering, During Retinoid-induced Maturation and Resistance of NB4 Promyelocytic Leukemia Cell Line" |
| 23 |
Butt, E.; Eigenthaler, M.; Genieser, H.-G., Eur. J. Pharmacol., 269, 265 - 268 (1994): "(Rp)-8-pCPT-cGMPS, a Novel cGMP-dependent Protein Kinase Inhibitor" |
| 22 |
Schultz, C.; Vajanaphanich, M.; Genieser, H.-G.; Jastorff, B.; Barrett, K.E.; Tsien, R.Y., Mol. Pharmacol., 46, 702 - 708 (1994): "Membrane-permeant Derivatives of Cyclic AMP Optimized for High Potency, Prolonged Activity, or Rapid Reversibility" |
| 21 |
Oegreid, D.; Dostmann, W.; Genieser, H.-G.; Niemann, P.; Doeskeland, S.O.; Jastorff, B., Eur. J. Biochem., 221, 1089 - 1094 (1994): "(Rp)- and (Sp)- 8- Piperidinoadenosine- 3', 5'- (cyclic) Thiophosphates Discriminate Completely Between Site A and B of the Regulatory Subunits of cAMP-dependent Protein Kinase Type I and II" |
| 20 |
Sollid, S.; Dostmann, W.R.G.; Genieser, H.-G.; Oegreid, D., Manuskript - Centre of Molecular Medicine Norway, 21 (1994): "(Rp)-Configurated Phophorothioate Analogs of cAMP are both Agonists and Antagonists of cAMP Action" |
| 19 |
Musgrave, I.F.; Genieser, H.-G.; Maronde, E.; Seifert, R., FEBS Lett., 318, 227 - 230 (1993): "Preparations of Rp- cyclic Adenosine 3', 5'- phosphorothioate (Rp-cAMPS) Can Contain Biologically Active Amounts of Adenosine" |
| 18 |
Schaap, P.; Van Ments-Cohen, M.; Soede, R.D.M.; Brandt, R.; Firtel, R.A.; Dostmann, W.; Genieser, H.-G.; Jastorff, B.; Van Haastert, P.J.M., J. Biol. Chem., 268, 6323 - 6331 (1993): "Cell-permeable Non-hydrolyzable cAMP Derivatives as Tools for Analysis of Signaling Pathways Controlling Gene Regulation in Dictyostelium" |
| 17 |
Jastorff, B.; Genieser, H.-G.; Cho-Chung, Y.S., Patent WO9321929 of November 11 (1993): "Phosphorothioate Derivatives of Cyclic AMP Analogues" |
| 16 |
Naß, N.; Colling, C.; Cramer, M.; Genieser, H.-G.; Butt, E.; Winkler, E.; Jaenicke, L.; Jastorff, B., Biochem. J., 285, 129 - 136 (1992): "Mapping of the Epitope/Paratope Interactions of a Monoclonal Antibody Directed Against Adenosine- 3', 5'- monophosphate" |
| 15 |
Yokozaki, H.; Tortora, G.; Pepe, S.; Maronde, E.; Genieser, H.-G.; Jastorff, B.; Cho- Chung, Y.S., Cancer Res., 52, 2504 - 2508 (1992): "Unhydrolysable Analogs of Cyclic Adenosine- 3', 5' - Monophosphate Demonstrating Growth Inhibition and Differentiation in Human Cancer Cells" |
| 14 |
Genieser, H.-G.; Winkler, E.; Butt, E.; Zorn, M.; Schulz, S.; Iwitzki, F.; Störmann, R.; Jastorff, B.; Doeskeland, S.O.; Oegreid, D.; Ruchaud, S.; Lanotte, M., Carbohydr. Res., 234, 217 - 235 (1992): "Derivates of 1-ß-D-Ribofuranosylbenzimidazole 3', 5'-phosphate that Mimic the Actions of Adenosine 3', 5',- phosphate (cAMP) and Guanosine 3', 5'- phosphate (cGMP)" |
| 13 |
Iwitzki, F.; van Bemmelen, M.X.P.; Genieser, H.-G.; Jastorff, B., Proc. Intl. Conf. Second Messengers Phosphoprot. UK (1992): "New Affinity Materials for Cyclic AMP Binding Proteins" |
| 12 |
Iwitzki, F.; van Bemmelen, M.X.P.; Genieser, H.-G.; Jastorff, B., 3rd Swed.- Germ. Workshop Nucleic Acid Synth. Struct. Funct. Sweden (1992): "cAMP Analogues Designed for Affinity Chromatography" |
| 11 |
Schultz, S.; Iwitzki, F.; Genieser, H.-G.; van Bemmelen, M.X.P.; Jastorff, B., 8th International Conference on Second Messengers & Phosphoproteins (1992): "cAMP Analogues Designed for Affinity Chromatography and CA Kinase Characterization" |
| 10 |
Van Ments-Cohen, M.; Genieser, H.-G.; Jastorff, B.; Van Haastert, P.J.M.; Schaap, P., FEMS Microbiol. Lett., 82, 9 - 14 (1991): "Kinetics and Nucleotide Specificity of a Surface cAMP Binding Site in Dictyostelium discoideum, which is not Down-regulated by cAMP" |
| 9 |
Sandberg, M.; Butt, E.; Nolte, C.; Fischer, L.; Halbrügge, M.; Beltmann, J.; Jahnsen, T.; Genieser, H.-G.; Jastorff, B.; Walter, U., Biochem. J., 279, 521 - 527 (1991): "Characterization of Sp- 5, 6- dichloro-1-ß-D-ribofuranosylbenzimidazole- 3',5'- monophosphorothioate (Sp-5,6-DCl-cBIMPS) as a Potent and Specific Activator of cyclic AMP- dependent Protein Kinase in Cell Extracts and Intact Cells" |
| 8 |
Van Lookeren Campagne, M.M.; Diaz, F.V.; Jastorff, B.; Winkler, E.; Genieser, H.-G.; Kessin, R.W., J. Biol. Chem., 265, 5847 - 5854 (1990): "Characterization of the Yeast Low Km cAMP- Phosphodiesterase With cAMP Analogues" |
| 7 |
Dostmann, W.R.G.; Taylor, S.S.; Genieser, H.-G.; Jastorff, B.; Doeskeland, S.O.; Oegreid, D., J. Biol. Chem., 265, 10484 - 10491 (1990): "Probing the Cyclic Nucleotide Binding Sites of cAMP-Dependent Protein Kinase I and II with Analogs of Adenosine- 3', 5'- Cyclic Phosphorothioates" |
| 6 |
Jastorff, B.; Butt, E.; Schultz, C.; Metschies, T.; Winkler, E.; Dostmann, W.; Walter, U.; van Bemmelen, M.; Genieser, H.-G., 7th International Conference on Second Messenger & Phosphoproteins Japan (1990): "A Rational Approach to Design Antagonists of Cyclic AMP, Cyclic GMP and 1, 4, 5 - IP3" |
| 5 |
Meijer, L.; Dostmann, W.; Genieser, H.-G.; Butt, E.; Jastorff, B., Develop. Biol., 133, 58 - 66 (1989): "Starfish Oocyte Maturation: Evidence for a Cyclic AMP-Dependent Inhibitory Pathway" |
| 4 |
Jastorff, B.; Genieser, H.-G.; Dostmann, W.; Bottin-Weber, U., Patent WO8907108 of August 10 (1989): "Process for Producing Nucleoside-3', 5'-Cyclophosphates and Nucleoside-3', 5'- Cyclothiophosphates" |
| 3 |
Genieser, H.-G.; Butt, E.; Bottin, U.; Jastorff, B., J. Syn. Org. Chem., 1 (1989): "Synthesis of the 3', 5'-Cyclic Phosphates from Unprotected Nucleosides" |
| 2 |
Dostmann, W.; Braumann, T.; Bottin, U.; Genieser, H.-G.; Stohrer, W.-D.; Jastorff, B., Universität Bremen (1989): "Mechanism of cAMP/Protein Kinase Type II Interactions: Studies with New cAMP Agonists and Antagonists" |
| 1 |
Genieser, H.-G.; Dostmann, W.; Bottin, U.; Butt, E.; Jastorff, B., Tetrahedron Lett., 29, 2803 - 2804 (1988): "Synthesis of Nucleoside-3', 5'-cyclic Phosphorotioates by Cyclothiophosphorylation of Unprotected Nucleosides" |

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