Collaborative Papers and Posters

91
 Bertinetti, D.; Schweinsberg, S.; Hanke, S. E.; Schwede, F.; Bertinetti, O.; Drewianka, S.; Genieser, H.-G.; Herberg, F.W., BMC Chem Biol, 9 (2009): "Chemical tools selectively target components of the PKA system"
90
 Chepurny, O.G.; Leech, C.A.; Kelley, G.G.; Dzhura, I.; Dzhura, E.; Li, X.; Rindler, M.J.; Schwede, F.; Genieser, H.-G.; Holz, G.G., J. Biol. Chem., 284, 10728 - 10736 (2009): "Enhanced Rap1 activation and insulin secretagogue properties of an acetoxymethyl ester of an Epac-selective cyclic AMP analog in rat INS-1 cells: Studies with 8-pCPT-2'-O-Me-cAMP-AM."
89
 Poppe, H.; Rybalkin, S.D.; Rehmann, H.; Hinds, T.R.; Tang, X.-B.; Christensen, A.E.; Schwede, F.; Genieser, H.-G.; Bos, J.L.; Doeskeland, S.O.; Hernandez, P.J.; Butt, E., Nature Methods, 5, 277 - 278 (2008): "Cyclic Nucleotide Analogs as Probes of Signaling Pathways"
88
 Schweinsberg, S.; Moll, D.; Burghardt, N.C.G.; Hahnefeld, C.; Schwede, F.; Zimmermann, B.; Drewianka, S.; Werner, L.; Kleinjung, F.; Genieser, H.-G.; Schuchhardt, J.; Herberg, F.W., Proteomics, 8, 1212 - 1220 (2008): "Systematic interpretation of cyclic nucleotide binding studies using KinetXBase"
87
 Moll, D.; Prinz, A.; Brendel, C.M.; Berrera, M.; Guske, K.; Zaccolo, M.; Genieser, H.-G.; Herberg, F.W., BMC Biochem., 9, 18 (2008): "Biochemical Characterization and Cellular Imaging of a Novel, Membrane Permeable Fluorescent cAMP Analog"
86
 Vliem, M.J.; Ponsioen, B.; Schwede, F.; Pannekoek, W.-J.; Riedl, J.; Kooistra, M.R.H:; Jalink, K.; Genieser, H.-G.; Bos, J.L.; Rehmann, H., ChemBioChem, 9, 2052 - 2054 (2008): "8-pCPT-2'-O-Me-cAMP-AM: An Improved Epac-selective cAMP Analogue"
85
 Rehmann, H.; Arias-Palomo, E.; Hadders, M.A.; Schwede, F.; Llorca, O.; Bos, J.L., Nature, 455, 124 - 127 (2008): "Structure of Epac2 in Complex with a cyclic AMP Analogue and RAP1B"
84
 Ouyang, M.; Zhang, L.; Zhu, J.; Schwede, F.; Thomas, S.A., PNAS, 105, 11993 - 11997 (2008): "Epac Signaling is Required for Hippocampus-dependent Memory Retrieval"
83
 Rodriguez-Collazo, P.; Snyder, S.K.; Chiffer, R.C.; Bressler, E.A.; Voss, T.C.; Anderson, E.P.; Genieser, H.-G.; Smith, C.L., Exp. Cell Res., 314, 2855 - 2869 (2008): "cAMP Signaling Regulates Histone H3 Phosphorylation and Mitotic Entry Through a Disruption of G2 Progression"
82
 Holz, G.G.; Chepurny, O.G.; Schwede, F.S., Cell. Signal., 20, 10 - 20 (2007): "Epac-selective cAMP Analogs: New Tools with which to Evaluate the Signal Transduction Properties of cAMP-regulated Guanine Nucleotide Exchange Factors"
81
 Biskup, C.; Kusch, J.; Schulz, E.; Nache, V.; Schwede, F.; Lehmann, F.; Hagen, V.; Benndorf, K., Nature, 446, 440 - 443 (2007): "Relating ligand binding to activation gating in CNGA2 channels"
80
 Laxman, S.; Riechers, A.; Sadilek, M.; Schwede, F.; Hernandez, P.J., PNAS, 103, 19194 - 19199 (2006): "Hydrolysis Products of cAMP Analogs Cause Transformation of Trypanosoma Brucei from slender to Stumpy-like Forms"
79
 Bryn, T.; Mahic, M.; Enserink, J.M.; Schwede, F.; Aandahl, E.M.; Tasken, K., J. Immunol., 176, 7361 - 7370 (2006): "The cyclic AMP-Epac1-Rap1 Pathway is Dissociated from Regulation of Effector Functions in Monocytes but Acquires Immunoregulatory Function in Mature Macrophages"
78
 Dao, K.K.; Teigen, K.; Kopperud, R.; Hodneland, E.; Schwede, F.; Christensen, A.E.; Martinez, A.; Doeskeland, S.O., J. Biol. Chem., 281, 21500 - 21511 (2006): "Epac1 and cAMP-dependent Protein Kinase Holoenzyme Have Similar cAMP Affinity, but Their cAMP Domains Have Distinct Structural Features and Cyclic Nucleotide Recognition"
77
 Kang, G.X.; Chepurny, O.G.; Malester, B.; Rindler, M.J.; Rehmann, H.; Barrere-Lemaire, S.; Schwede, F.; Coetzee, W.A.; Holz, G.G., J. Physiol.-London, 573, 595 - 609 (2006): "cAMP Sensor Epac as a Determinant of ATP-sensitive Potassium Channel Activity in Human Pancreatic Beta Cells and Rat INS-1 Cells"
76
 Makarevich, A.V.; Sirotkin, A.V.; Genieser, H.-G., Anim. Reprod. Sci., 81, 125 - 136 (2004): "Action of Protein Kinase A Regulators on Secretory Activity of Porcine Granulosa Cells in Vitro"
75
 Mahic, M.; Bryn, T.; Enserink, J.; Schwede, F.; Aandahl, E.M.; Tasken, K., Poster #THP019 Montreal, 12 (2004): "Modulation of Monocyte Activation by Cyclic AMP is Mainly Mediated Through Protein Kinase A"
74
 Selheim, F.; Krakstad, C.; Christensen, A.-E.; Hagland, H.; Schwede, F.; Genieser, H.-G.; Doeskeland, S.O., Poster # THP017 Montreal, 12 (2004): "The cAMP Receptor Epac Has a Permissive Role for cAMP-dependent Protein Kinase Action to Protect PC-12 Pheochromocytoma Cells Against Stress-induced Apoptosis and Induce Neuronal Differentiation"
73
 Genieser, H.-G.; Barrere-Lemaire, S.; Christensen, A.E.; Doeskeland, S.O.; Havemann, U.; Manzau, U.; Schwede, F.; Rehmann, H., Poster #THP016 Montreal, 12 (2004): "Analogues of Cyclic AMP to Distinguish Between PKA and Epac"
72
 Weissinger, E.M.; Oettrich, K.; Genieser, H.-G.; Schwede, F.; Dangers, M.; Dammann, E.; Kolb, H.-J.; Mischak, H.; Ganser, A.; Kolch, W., Brit. J. Cancer, 91, 186 - 192 (2004): "Activation of Protein Kinase A (PKA) by 8-Cl-cAMP as a Novel Approach for Antileukaemic Therapy"
71
 Kang, G.; Joseph, J.W.; Chepurny, O.G.; Monaco, M.; Wheeler, M.B.; Barrere-Lemaire, S.; Schwede, F.; Genieser, H.-G.; Holz, G.G., J. Biol. Chem., 278, 8279 - 8285 (2003): "Epac-Selective cAMP Analog 8-pCPT-2'-O-Me-cAMP As A Stimulus For Ca 2+ -Induced Ca 2+ Release And Exocytosis In Pancreatic Beta-Cells"
70
 Rangarajan, S.; Enserink, J.M.; Kuiperij, H.B.; de Rooij, J.; Price, L.S.; Schwede, F.; Barrere-Lemaire, S., J. Cell Biol., 160, 487 - 493 (2003): "Cyclic AMP Induces Integrin-mediated Cell Adhesion Through Epac and Rap1 Upon Stimulation of the ß2-Adrenergic Receptor"
69
 Rehmann, H.; Schwede, F.; Doeskeland, S.O.; Wittinghofer, A.; Barrere-Lemaire, S., J. Biol. Chem., 278, 38548 - 38556 (2003): "Ligand-mediated Activation of the cAMP-responsive Guanine Nucleotide Exchange Factor Epac"
68
 Bartsch, M.; Zorn-Kruppa, M.; Kühl, N.; Genieser, H.-G.; Schwede, F.; Jastorff, B., Biol. Chem., 384, 1321 - 1326 (2003): "Bioactivatable, Membrane-permeant Analogs of Cyclic Nucleotides as Biological Tools for Growth Control of C6 Glioma Cells"
67
 Christensen, A.E.; Selheim, F.; de Rooij, J.; Dremier, S.; Schwede, F.; Dao, K.K.; Martinez, A.; Maenhaut, C.; Barrere-Lemaire, S.; Genieser, H.-G.; Doeskeland, S.O., J. Biol. Chem., 278, 35394 - 35402 (2003): "cAMP Analog Mapping of Epac1 and cAMP-Kinase. Discriminating Analogs Demonstrate that Epac and cAMP-Kinase Act Synergistically to Promote PC-12 Cell Neurite Extension"
66
 Christensen, A.E.; de Rooij, J.; Kopperud, R.; Nilsen, O. K.; Dao, K.K.; Schwede, F.; Barrere-Lemaire, S.; Genieser, H.-G.; Doeskeland, S.O., Abstract of the 13th Protein Kinase Symposium, 5 - 5 (2002): "Comparison of the cAMP Binding Sites of EPAC-1 and cAMP-Kinase"
65
 Enserink, J.M.; Christensen, A.E.; de Rooij, J.; van Triest, M.; Schwede, F.; Genieser, H.-G.; Doeskeland, S.O.; Blank, J.L.; Barrere-Lemaire, S., Nature Cell Biol., 4, 901 - 906 (2002): "A Novel Epac-specific cAMP Analogue Demonstrates Independent Regulation of Rap 1 and ERK"
64
 Sirotkin, A.V.; Makarevich, A.V.; Pivko, J.; Genieser, H.-G., Asian-Aust. J. Anim. Sci., 15, 1045 - 1050 (2002): "Intracellular Mechanisms of Growth Hormone Action on Apoptosis in Cultured Porcine Ovarian Granulosa Cells"
63
 Sirotkin, A.V.; Makarevich, A.V.; Kwon, H. B.; Kotwica, J.; Genieser, H.-G.; Pivko, J., Endocrine Abstracts, 4, 79 (2002): "Effect of Growth Hormone on Porcine Ovarian Cells and its Intracellular Mechanisms"
62
 Maronde, E.; Korf, H.-W.; Niemann, P.; Genieser, H.-G., J. Pineal Res., 31, 183 - 185 (2001): "Direct Comparison of the Potency of Three Novel cAMP Analogs to Induce CREB-Phosphorylation in Rat Pinealocytes"
61
 Wätjen, W.; Benters, J.; Haase, H.; Schwede, F.; Jastorff, B.; Beyersmann, D., Toxicol., 157, 167 - 175 (2001): "Zn2+ and Cd2+ Increase the cyclic GMP level in PC12 Cells by Inhibition of the cyclic Nucleotide Phosphodiesterase"
60
 Schwede, F.; Christensen, A.; Liauw, S.; Hippe, T.; Kopperud, R.; Jastorff, B.; Doeskeland, S.O., Biochemistry, 39, 8803 - 8812 (2000): "8-Substituted cAMP Analogues Reveal Marked Differences in Adaptability, Hydrogen Bonding, and Charge Accomodation between Homologous Binding Sites (AI/AII and BI/BII) in cAMP Kinase I and II"
59
 Sirotkin, A.V.; Mertin, D.; Süvegova, K.; Makarevich, A.V.; Genieser, H.-G.; Luck, M.R.; Osadchuk, L.V., Gen. Comp. Endocrinol., 117, 207 - 217 (2000): "Effect of Restricted Food Intake on Production, Catabolism, and Effects of IGF-I and Cyclic Nucleotides in Cultured Ovarian Tissue of Domestic Nutria (Myocastor coypus)"
58
 Schwede, F.; Brustugun, O.T.; Zorn-Kruppa, M.; Doeskeland, S.O.; Jastorff, B., Bioorg. Med. Chem. Lett., 10, 571 - 573 (2000): "Membrane-permeant, Bioactivatable Analogues of cGMP as Inducers of Cell Death in IPC-81 Leukemia Cells"
57
 Sirotkin, A.V.; Makarevich, A.V.; Genieser, H.-G.; Kotwica, J.; Hetenyi, L., Exp. Clin. Endocrinol. Diabetes, 108, 214 - 219 (2000): "Effect of four cGMP Analogues with Different Mechanisms of Action on Hormone Release by Porcine Ovarian Granulosa Cells In Vitro"
56
 Christensen, A.; Dao, K.K.; Doeskeland, S.O.; Schwede, F.; Jastorff, B.; Genieser, H.-G.; de Rooij, J.; Bos, J.; Rehmann, H.; Kraemer, A.; Wittinghofer, A., 12th Protein Kinase Symp. "NO/cGMP and Protein Kinase Signaling" Bad Brückenau/Germany (2000): "8-Modified cAMP Analogs give Insight into the Geometries of the cAMP Binding Sites of RI, RII and EPAC-1"
55
 Schwede, F.; Maronde, E.; Genieser, H.-G.; Jastorff, B., Pharmacol. Ther., 87, 199 - 226 (2000): "Cyclic Nucleotide Analogs as Biochemical Tools and Prospective Drugs"
54
 Sirotkin, A.V.; Makarevich, A.V.; Pivko, J.; Kotwica, J.; Genieser, H.-G.; Bulla, J., J. Steroid Biochem. Mol. Biol., 74, 1 - 9 (2000): "Effect of cGMP Analogues and Protein Kinase G Blocker on Secretory Activity, Apoptosis and the cAMP/Protein Kinase A System in Porcine Ovarian Granulosa Cells In Vitro"
53
 Sirotkin, A.V.; Mertin, D.; Süvegova, K.; Makarevich, A.V.; Genieser, H.-G.; Osadchuk, L.V., Animal Production Review (2000): "The Cyclic Nucleotide-IGF-I System as Possible Mediator of Effect of Nutrition on Ovarian Activity in Domestic Nutria (Myocastor coypus)"
52
 Maronde, E.; Wicht, H.; Tasken, K.; Genieser, H.-G.; Dehghani, F.; Olcese, J.; Korf, H.W., J. Pineal Res., 27, 170 - 182 (1999): "CREB Phosphorylation and Melatonin Biosynthesis in the Rat Pineal Gland: Involvement of cyclic AMP-dependent Protein KinaseType II"
51
 Sirotkin, A.; Makarevich, A.; Kotwica, J.; Genieser, H.-G.; Bulla, J., J. Farm. Animal. Sci., 32, 11 - 14 (1999): "Effect of Chemical Analogues of cAMP and cGMP on Hormone and Growth Factor Secretion by Porcine Ovarian Cells"
50
 Mertin, D.; Sirotkin, A.V.; Süvegova, K.; Makarevich, A.V.; Genieser, H.-G.; Luck, M.R.; Osadchuk, L.V., Society for the Study of Fertility Aberystwyth (1999): "The Cyclic Nucleotide - IGF-I System as a Possible Link Between Nutrion and Reproduction in Domestic Nutria"
49
 Schwede, F.; Genieser, H.-G.; Jastorff, B., Cell. Mol. Biol. Lett., 4, 466 (1999): "Cyclic Nucleotide Analogs as Prospective Drugs"
48
 Walton, T.J.; Bayliss, M.A.; Pereira, M.L.; Games, D.E.; Genieser, H.-G.; Brenton, A.G.; Harris, F.M.; Newton, R.P., Rapid Commun. Mass Spectrom., 12, 449 - 455 (1999): "Fast-atom Bombardment Tandem Mass Spectrometry of Cyclic Nucleotide Analogues Used as Site-selective Activators of Cyclic Nucleotide-dependent Protein Kinases"
47
 Sirotkin, A.; Makarevic, A.; Chribikova, J.; Genieser, H.-G.; Taradajnik, T.; Marnet, P.-G.; Chrenek, P.; Schaeffer, H.-J.; Mlyncek, M.; Kubek, A.; Bulla, J., Journal for Agricultural Sciences, 43, 391 - 398 (1999): "Secretion and Effects of Growth Factors in Farm Animal and Human Ovaries"
46
 Wei, J.Y.; Cohen, E.D.; Genieser, H.-G.; Barnstable, C.J., J. Mol. Neurosci., 10, 53 - 64 (1998): "Substituted cGMP Analogs Can Act as Selective Agonists of the Rod Photoreceptor cGMP-Gated Cation Channel"
45
 Hebert, M.C.; Schwede, F.; Jastorff, B.; Cote, R.H., J. Biol. Chem., 273, 5557 - 5565 (1998): "Structural Features of the Noncatalytic cGMP Binding Sites of Frog Photoreceptor Phoshodiesterase Using cGMP Analogs"
44
 Vaandrager, A.B.; Edixhoven, M.; Bot, A.G.M.; Kroos, M.A.; Jarchau, T.; Lohmann, S.; Genieser, H.-G.; Dejonge, H.R., J. Biol. Chem., 272, 11816 - 11823 (1997): "Endogenous Type II cGMP-Dependent Protein Kinase Exists as a Dimer in Membranes and can be Functionally Distinguished from the Type I Isoforms"
43
 Kraß, J.; Jastorff, B.; Genieser, H.-G., Anal. Chem., 69, 2575 - 2581 (1997): "Determination of Lipophilicity by Gradient Elution High-Performance Liquid Chromatography"
42
 Kruppa, J.; Keely, S.; Schwede, F.; Schultz, C.; Barrett, K.E.; Jastorff, B., Bioorg. Medicinal Chem. Lett., 7, 945 - 948 (1997): "Bioactivatable Derivatives of 8- Substituted cAMP- Analogues"
41
 Genieser, H.-G.; Walter, U.; Butt, E., US Patent 5056 of April 29, 625 (1997): "Derivatives of Cyclic Guanosine-3',5'-Monophosphorothioate"
40
 Sirotkin, A.V.; Makarevic, A.V.; Genieser, H.-G., 3rd Intl. Conf. Cyclic Nucleotide Phosphodiesterases ( From Genes to Therapies ) Scotland (1996): "The Effect of PDE Inhibitors and Other Regulators of PKA on the Secretory Activity of Porcine Ovarian Granulosa Cells"
39
 Sirotkin, A.V.; Makarevic, A.V.; Genieser, H.-G., J. Physiol. Pharmacol., 47, 134 (1996): "Effect of Regulators of Protein Kinase A on IGF-I and Steroid Secretion by Porcine Granulosa Cells in Vitro"
38
 Kroner, C.; Boekhoff, I.; Lohmann, S.M.; Genieser, H.-G.; Breer, H., Eur. J. Biochem., 236, 632 - 637 (1996): "Regulation of Olfactory Signalling Via cGMP-dependent Protein Kinase"
37
 Wei, J.Y.; Cohen, E.D.; Yan, Y.-Y.; Genieser, H.-G.; Barnstable, C.J., Biochemistry, 35, 16815 - 16823 (1996): "Identification of Competitive Antagonists of the Rod Photoreceptor cGMP-Gated Cation Channel: Beta-Phenyl-1,N(2)-Etheno-Substituted cGMP Analogues as Probes of the cGMP-Binding Site"
36
 Wei, J.Y.; Cohen, E.D.; Yan, Y.-Y.; Genieser, H.-G.; Barnstable, C.J., American Society for Neuroscience, 880 (1996): "PET-substituted cGMP Analogs: Novel Antagonists of Rod Photoreceptor cGMP-gated Channel"
35
 Schwede, F., Ph.D. Thesis (1996): "Synthese und Eigenschaften ausgewählter Analoga von cGMP und ihr Einsatz in der biologischen Forschung"
34
 Sirotkin, A.V.; Makarevich, A.V.; Genieser, H.-G., J. Physiol. Pharmacol., 47, 134 (1996): "Effect of Regulators of Protein Kinase A on IGF-I and Steroid Secretion by Porcine Granulosa Cells in Vitro"
33
 Hoffmann, C.; Genieser, H.-G.; Veron, M.; Jastorff, B., Bioorg. Med. Chem. Lett., 6, 2571 - 2574 (1996): "Novel Synthesis of Nucleoside 5'-Polyphosphates"
32
 Gjertsen, B.T.; Mellgren, G.; Otten, A.; Maronde, E.; Genieser, H.-G.; Jastorff, B.; Vintermyr, O.; McKnight, G.S.; Doeskeland, S.O., J. Biol. Chem., 270, 20599 - 20607 (1995): "Novel (Rp)-cAMPS Analogs as Tools for Inhibition of cAMP-Kinase in Cell Culture"
31
 Ruchaud, S.; Zorn, M.; Davilar-Villar, E.; Genieser, H.-G.; Hoffmann, C.; Gjertsen, B.T.; Doeskeland, S.O.; Jastorff, B.; Lanotte, M., Cell. Pharmacol., 2, 127 - 140 (1995): "Evidence for Several Pathways of Biological Response to Hydrolysable cAMP-Analogues Using a Model System of Apoptosis in IPC-81 Leukaemia Cells"
30
 Gjertsen, B.T.; Mellgren, G.; Vintermyr, O.K.; Genieser, H.-G.; Jastorff, B.; Doeskeland, S.O., Int. Conference on Second Messenger & Phosphoproteins TN USA (1995): "The Basal cAMP-Dependent Protein Kinase (cAK) Activity in Resting Hepatocytes Can Be inhibited By Rp-8-Br-cAMPS, and Has a Permissive Role For IL-1ß Action"
29
 Butt, E.; Pöhler, D.; Genieser, H.-G.; Huggins, J.P.; Ristorcelli, E., Br. J. Pharmacol., 116, 3110 - 3116 (1995): "Inhibition of Cyclic GMP-dependent Protein Kinase-mediated Effects by (Rp)-8-bromo-PET- cyclic GMPS"
28
 Genieser, H.-G., Proc. 9. Int. Conf. Second Mess. & Phosphoprot. TN USA (1995): "Lipophilic Ranking of Biologically Important Cyclic Nucleotides"
27
 Genieser, H.-G.; Ristorcelli, E.; Butt, E., 9 th International Conference on Second Messenger & Phosphoproteins (1995): "Rp-8-Br-PET-cGMPS, A New Potent Inhibitor of Cyclic GMP-dependent Protein Kinase"
26
 Ruchaud, S.; Duprez, E.; Gendron, M.C.; Houge, G.; Genieser, H.-G.; Jastorff, B.; Doeskeland, S.O.; Lanotte, M., Proc. Natl. Acad. Sci. USA, 91, 8428 - 8432 (1994): "Two Distinctly Regulated Events, Priming and Triggering, During Retinoid-induced Maturation and Resistance of NB4 Promyelocytic Leukemia Cell Line"
25
 Butt, E.; Eigenthaler, M.; Genieser, H.-G., Eur. J. Pharmacol., 269, 265 - 268 (1994): "(Rp)-8-pCPT-cGMPS, a Novel cGMP-dependent Protein Kinase Inhibitor"
24
 Schultz, C.; Vajanaphanich, M.; Genieser, H.-G.; Jastorff, B.; Barrett, K.E.; Tsien, R.Y., Mol. Pharmacol., 46, 702 - 708 (1994): "Membrane-permeant Derivatives of Cyclic AMP Optimized for High Potency, Prolonged Activity, or Rapid Reversibility"
23
 Oegreid, D.; Dostmann, W.; Genieser, H.-G.; Niemann, P.; Doeskeland, S.O.; Jastorff, B., Eur. J. Biochem., 221, 1089 - 1094 (1994): "(Rp)- and (Sp)- 8- Piperidinoadenosine- 3', 5'- (cyclic) Thiophosphates Discriminate Completely Between Site A and B of the Regulatory Subunits of cAMP-dependent Protein Kinase Type I and II"
22
 Sollid, S.; Dostmann, W.R.G.; Genieser, H.-G.; Oegreid, D., Manuskript - Centre of Molecular Medicine Norway, 21 (1994): "(Rp)-Configurated Phophorothioate Analogs of cAMP are both Agonists and Antagonists of cAMP Action"
21
 Musgrave, I.F.; Genieser, H.-G.; Maronde, E.; Seifert, R., FEBS Lett., 318, 227 - 230 (1993): "Preparations of Rp- cyclic Adenosine 3', 5'- phosphorothioate (Rp-cAMPS) Can Contain Biologically Active Amounts of Adenosine"
20
 Schaap, P.; Van Ments-Cohen, M.; Soede, R.D.M.; Brandt, R.; Firtel, R.A.; Dostmann, W.; Genieser, H.-G.; Jastorff, B.; Van Haastert, P.J.M., J. Biol. Chem., 268, 6323 - 6331 (1993): "Cell-permeable Non-hydrolyzable cAMP Derivatives as Tools for Analysis of Signaling Pathways Controlling Gene Regulation in Dictyostelium"
19
 Cho-Chung, Y.S.; Genieser, H.-G.; Jastorff, B., Patent WO9321929 of November 11 (1993): "Phosphorothioate Derivatives of Cyclic AMP Analogues"
18
 Naß, N.; Colling, C.; Cramer, M.; Genieser, H.-G.; Butt, E.; Winkler, E.; Jaenicke, L.; Jastorff, B., Biochem. J., 285, 129 - 136 (1992): "Mapping of the Epitope/Paratope Interactions of a Monoclonal Antibody Directed Against Adenosine- 3', 5'- monophosphate"
17
 Cho-Chung, Y.S.; Jastorff, B.; Genieser, H.-G., USA patent 5916, 843 (1992): "Cyclic AMP Analogues, Individually and in Pairs, to Inhibit Neoplastic Cell Growth"
16
 Yokozaki, H.; Tortora, G.; Pepe, S.; Maronde, E.; Genieser, H.-G.; Jastorff, B.; Cho- Chung, Y.S., Cancer Res., 52, 2504 - 2508 (1992): "Unhydrolysable Analogs of Cyclic Adenosine- 3', 5' - Monophosphate Demonstrating Growth Inhibition and Differentiation in Human Cancer Cells"
15
 Genieser, H.-G.; Winkler, E.; Butt, E.; Zorn, M.; Schulz, S.; Iwitzki, F.; Störmann, R.; Jastorff, B.; Doeskeland, S.O.; Oegreid, D.; Ruchaud, S.; Lanotte, M., Carbohydr. Res., 234, 217 - 235 (1992): "Derivates of 1-ß-D-Ribofuranosylbenzimidazole 3', 5'-phosphate that Mimic the Actions of Adenosine 3', 5',- phosphate (cAMP) and Guanosine 3', 5'- phosphate (cGMP)"
14
 Iwitzki, F.; van Bemmelen, M.X.P.; Genieser, H.-G.; Jastorff, B., Proc. Intl. Conf. Second Messengers Phosphoprot. UK (1992): "New Affinity Materials for Cyclic AMP Binding Proteins"
13
 Iwitzki, F.; van Bemmelen, M.X.P.; Genieser, H.-G.; Jastorff, B., 3rd Swed.- Germ. Workshop Nucleic Acid Synth. Struct. Funct. Sweden (1992): "cAMP Analogues Designed for Affinity Chromatography"
12
 Schultz, S.; Iwitzki, F.; Genieser, H.-G.; van Bemmelen, M.X.P.; Jastorff, B., 8th International Conference on Second Messengers & Phosphoproteins (1992): "cAMP Analogues Designed for Affinity Chromatography and CA Kinase Characterization"
11
 Van Ments-Cohen, M.; Genieser, H.-G.; Jastorff, B.; Van Haastert, P.J.M.; Schaap, P., FEMS Microbiol. Lett., 82, 9 - 14 (1991): "Kinetics and Nucleotide Specificity of a Surface cAMP Binding Site in Dictyostelium discoideum which is not Down-regulated by cAMP"
10
 Sandberg, M.; Butt, E.; Nolte, C.; Fischer, L.; Halbrügge, M.; Jahnsen, T.; Genieser, H.-G.; Jastorff, B.; Walter, U., Biochem. J., 279, 521 - 527 (1991): "Characterization of Sp- 5, 6- dichloro-1-ß-D-ribofuranosylbenzimidazole- 3',5'- monophosphorothioate (Sp-5,6-DCl-cBIMPS) as a Potent and Specific Activator of cyclic AMP- dependent Protein Kinase in Cell Extracts and Intact Cells"
9
 Van Lookeren Campagne, M.M.; Diaz, F.V.; Jastorff, B.; Winkler, E.; Genieser, H.-G.; Kessin, R.W., J. Biol. Chem., 265, 5847 - 5854 (1990): "Characterization of the Yeast Low Km cAMP- Phosphodiesterase With cAMP Analogues"
8
 Dostmann, W.R.G.; Taylor, S.S.; Genieser, H.-G.; Jastorff, B.; Doeskeland, S.O.; Oegreid, D., J. Biol. Chem., 265, 10484 - 10491 (1990): "Probing the Cyclic Nucleotide Binding Sites of cAMP-Dependent Protein Kinase I and II with Analogs of Adenosine- 3', 5'- Cyclic Phosphorothioates"
7
 Oegreid, D.; Dostmann, W.; Doeskeland, S.O.; Genieser, H.-G.; Jastorff, B.; Taylor, S., 7th International Conference of Cyclic Nucleotides (1990): "Comparison of the Two Classes of Binding Sites (A and B) of Type I and Type II cAMP-dependent Protein Kinases by Using Phosphorothioate Analogs of cAMP"
6
 Jastorff, B.; Butt, E.; Schultz, C.; Metschies, T.; Winkler, E.; Dostmann, W.; Walter, U.; Van Bemmelen, M.; Genieser, H.-G., 7th International Conference on Second Messenger & Phosphoproteins Japan (1990): "A Rational Approach to Design Antagonists of Cyclic AMP, Cyclic GMP and 1, 4, 5 - IP3"
5
 Meijer, L.; Dostmann, W.; Genieser, H.-G.; Butt, E.; Jastorff, B., Develop. Biol., 133, 58 - 66 (1989): "Starfish Oocyte Maturation: Evidence for a Cyclic AMP-Dependent Inhibitory Pathway"
4
 Jastorff, B.; Genieser, H.-G.; Dostmann, W.; Bottin-Weber, U., Patent WO8907108 of August 10 (1989): "Process for Producing Nucleoside-3', 5'-Cyclophosphates and Nucleoside-3', 5'- Cyclothiophosphates"
3
 Genieser, H.-G.; Butt, E.; Bottin, U.; Dostmann, W.; Jastorff, B., J. Syn. Org. Chem., 1 (1989): "Synthesis of the 3', 5'-Cyclic Phosphates from Unprotected Nucleosides"
2
 Dostmann, W.; Braumann, T.; Bottin, U.; Genieser, H.-G.; Stohrer, W.-D.; Jastorff, B., Universität Bremen (1989): "Mechanism of cAMP/Protein Kinase Type II Interactions: Studies with New cAMP Agonists and Antagonists"
1
 Genieser, H.-G.; Dostmann, W.; Bottin, U.; Butt, E.; Jastorff, B., Tetrahedron Lett., 29, 2803 - 2804 (1988): "Synthesis of Nucleoside-3', 5'-cyclic Phosphorotioates by Cyclothiophosphorylation of Unprotected Nucleosides"

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Last modified: January 28, 2008