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Sp-GTP-α-S

Guanosine- 5'- O- (1- thiotriphosphate), Sp isomer ( Sp-GTP-α-S ), sodium salt
Cat. No.: G 015
    
CAS No.: [81570-51-6]
Shipping: Dry ice
Product Name Price (net) Qty
Cat. No.: G 015-05
Unit: 5 µmol / ~2.7 mg
$229.00

For other salt forms or a guaranteed higher purity please inquire.
Useful for modulation of GTP-responsive receptors and determination of their stereospecificity (Eckstein, F.,  Ann. Rev. Biochem., 54, 367 - 402 (1985)). Increased metabolic stability compared to GTP. Accepted by RNA polymerase for incorporation of phosphorothioate into RNA, by guanylate cyclase for cyclisation to Sp-cGMPS and by tubulin (Xu et al., Biochim. Biophys. Acta, 1383, 111 - 122 (1998)). Detailed technical information available.

 

Vial containing 500 µl of 10 mM aqueous solution of pH 7.6

Cat. No. G 015
CAS number [81570-51-6]
Purity > 95% HPLC
Salt form Sodium
Appearance 10 mM aqueous solution of pH 7.6
Storage temperature -70°C / -94°F
Molecular formula C₁₀H₁₆N₅O₁₃P₃S (free acid)
Molecular weight [g/mol] 539,3 (free acid)
Absorption max [nm] 252
Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] 14300
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