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Sp-dUTP-α-S

2'- Deoxyuridine- 5'- O- (1- thiotriphosphate), Sp-isomer (Sp-dUTP-α-S)
Cat. No.: D 049
    
CAS No.: [876068-87-0]
Shipping: Dry ice
Product Name Price (net) Qty
Cat. No.: D 049-05
Unit: 5 µmol / ~2.4 mg
$340.00

For other salt forms or a guaranteed higher purity please inquire. Detailed technical information available. Reference: Bergman et al., FEBS Lett., 441, 327 - 330 (1998).

 

Vial containing 500 µl of 10 mM aqueous solution of pH 7.6

Cat. No. D 049
CAS number [876068-87-0]
Purity > 95% HPLC
Salt form Sodium
Appearance 10 mM aqueous solution of pH 7.6
Storage temperature -70°C / -94°F
Molecular formula C₉H₁₁N₂O₁₃P₃S (free acid)
Molecular weight [g/mol] 484.2 (free acid)
Absorption max [nm] 262
Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] 10000
  • 1. Jacobson K. A., Costanzi S., Ivanov A. A., Tchilibon S., Besada P., Gao Z.-G., Maddileti S.Harden T. K., Biochem. Pharmacol., 71, 540 - 549 (2006), "Structure Activity and Molecular Modeling Analyses of Ribose- and Base-modified Uridine 5'-triphosphate Analogues at the Human P2Y2 and P2Y4 Receptors"
  • 2. Ryder S. P.Strobel S. A., Methods Enzymol., 18, 38 - 50 (1999), "Nucleotide Analog Interference Mapping"
  • 3. Bergman A.-C., Nyman P. O.Larsson G., FEBS Lett., 441, 327 - 330 (1998), "Kinetic Properties and Stereospecificity of the Monomeric dUTPase from Herpes Simplex Virus Type I"
  • 4. Goody R., Isakov M.Labeit S., Ger. Offen. DE 3374, 546, 0 - 0 (1985), "DNA Sequencing Involving Alpha-thiodeoxyribonucleotide triphosphate-labeled DNA and Exonuclease Digestion, Synthesis of Alpha-thionucleotide triphosphates and Resolution of the Resulting Diastereomeric Mixture"