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Alternative structural projections:

Sp-cAMPS, sodium salt

Adenosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer ( Sp-cAMPS ), sodium salt
PDE-resistant PKA agonist
Cat. No.: A 003 S
CAS No.: [71774-13-5]
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Product Name Price (net) Qty
Cat. No.: A 003-10 S
Unit: 10 µmol / ~3.7 mg

Specially purified: Corresponding Rp-isomer below detection limits. For other salt forms please inquire. Activator of protein kinase A (cyclic AMP agonist). Considerably higher resistance against cyclic nucleotide phosphodiesterases compared to dibutyryl or 8-Br-cAMP, no metabolic side effects. Membrane permeability comparable to 8-Br-cAMP. Detailed technical information and updated reference list available on request. Reference: Tsien et al.: J. Cell Biol., 117, 57 - 72 (1992).

Cat. No. A 003 S
CAS number [71774-13-5]
Purity > 99% HPLC
Salt form Sodium
Storage temperature -20°C / -4°F
Molecular formula C₁₀H₁₁N₅O₅PS · Na
Molecular weight [g/mol] 367,3
cAMP modified at the exocyclic oxygen axial (Sp-)
Target PKA (cAK) Activator
Lipophilicity 1.31
Absorption max [nm] 259
Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] 15200