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Alternative structural projections:

Sp-8-AEA-cAMPS-Agarose

8- (2- Aminoethylamino)adenosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer, immobilized on agarose gel ( Sp-8-AEA-cAMPS-Agarose )
Hydrolysis-resistant Sp-cAMPS immobilized on agarose gel 
Cat. No.: A 008
    
CAS No.: [pending]
Shipping: ambient
Product Name Price (net) Qty
Cat. No.: A 008-06
Unit: 0.6 ml
$223.00
Cat. No.: A 008-25
Unit: 2.5 ml
$694.00
Cat. No.: A 008-60
Unit: 6 ml
$1,351.00
The protein kinase A activator Sp-cAMPS (Cat. No. A 003) immobilized on agarose by an aminoethylamino spacer attached to position 8 of the ligand. Free Sp-cAMPS is only very slowly metabolized by mammalian phosphodiesterases and thus represents an extraordinary stable ligand. In addition, its reduced binding affinity towards protein kinase A compared to cAMP results in milder desorption conditions during affinity chromatography. The gel can be used for affinity chromatography of various cyclic nucleotide-responsive proteins such as protein kinases, phosphodiesterases and others. This ligand is offered with a longer spacer (Sp-8-AHA-cAMPS-Agarose, Cat. No. A 013) as well. Detailed technical information available. Reference: Bertinetti et al., BMC Chem. Biol, 9 (2009).

Normally all affinity gels are supplied in pre-packed columns. The free beads without a column are available upon request.
Cat. No. A 008
CAS number [pending]
Storage temperature 4°C / 39°F
cAMP modified at the exocyclic oxygen axial (Sp-)
Modifications 8-cAMP