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Alternative structural projections:

Sp-6-Bnz-cAMPS

N6- Benzoyladenosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer ( Sp-6-Bnz-cAMPS ), sodium salt

PDE-resistant form of 6-Bnz-cAMP
Cat. No.: B 040
    
CAS No.: [152218-18-3]
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Product Name Price (net) Qty
Cat. No.: B 040-05
Unit: 5 µmol / ~2.4 mg
$248.00
Site-selective, PDE-resistant and membrane-permeant activator of cAMP-dependent protein kinase. Sp-6-Bnz-cAMPS does not activate Epac and thus can be used as an Epac-negative control. For more details on site selectivity please inquire. Detailed technical information available. Reference: Lim et al., Neurosci. Lett., 479, 13 - 17 (2010).
Cat. No. B 040
CAS number [152218-18-3]
Purity > 98% HPLC
Salt form Sodium
Storage temperature -20°C / -4°F
Molecular formula C₁₇H₁₅N₅O₆PS · Na
Molecular weight [g/mol] 471,4
cAMP modified at the exocyclic oxygen axial (Sp-)
Target PKA (cAK) Activator
Lipophilicity 2.15
Absorption max [nm] 279
Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] 17000
  • 1. Lim J.-G., Lee J.-J., Park S.-H., Park J.-H., Kim S.-J., Cho H.-C., Baek W.-K., Kim D.-K.Song D.-K., Neurosci. Lett., 479, 13 - 17 (2010), "Glucagon-like Peptide-1 Protecs NSC-34 Motor Neurons against Glucosamine through Epac-mediated Uptake Enhancement"
  • 2. Ouyang M., Zhang L., Zhu J. J., Schwede F.Thomas S. A., PNAS, 105, 11993 - 11997 (2008), "Epac Signaling is Required for Hippocampus-dependent Memory Retrieval"