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Sp-2-AHA-cAMPS

2- (6- Aminohexylamino)adenosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer ( Sp-2-AHA-cAMPS )
PDE-resistant Sp-cAMPS functionalized for immobilization or conjugation with markers and dyes
Cat. No.: A 068
    
CAS No.: [214276-94-5]
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Product Name Price (net) Qty
Cat. No.: A 068-05
Unit: 5 µmol / ~2.3 mg
$289.00
Phosphodiesterase-resistant ligand for affinity chromatography of cAMP and cGMP binding proteins and suitable for modification with fluorophores and other markers. PDE-resistant form of 2-AHA-cAMP (Cat. No. A 053). Detailed technical information available. This ligand is also available with a shorter spacer (Sp-2-AEA-cAMPS, Cat. No. A 093).
Cat. No. A 068
CAS number [214276-94-5]
Purity > 98% HPLC
Salt form Free acid
Storage temperature -20°C / -4°F
Molecular formula C₁₆H₂₆N₇O₅PS
Molecular weight [g/mol] 459,5
cAMP modified at the exocyclic oxygen axial (Sp-)
Modifications 2-cAMP
Target PKA (cAK) Activator
Lipophilicity 1.70
Absorption max [nm] 258
Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] 12600
  • 1. Bertinetti D., Schweinsberg S., Hanke S. E., Schwede F., Bertinetti O., Drewianka S., Genieser H.-G.Herberg F. W., BMC Chem Biol, 9, 0 - 0 (2009), "Chemical tools selectively target components of the PKA system"