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Alternative structural projections:

Rp-2-Cl-cAMPS

2- Chloroadenosine- 3', 5'- cyclic monophosphorothioate, Rp- isomer ( Rp-2-Cl-cAMPS ), sodium salt
Cat. No.: C 073
    
CAS No.: [124844-92-4]
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Product Name Price (net) Qty
Cat. No.: C 073-05
Unit: 5 µmol
$328.00
For other salt forms please inquire. Analogue of the protein kinase A inhibitor Rp-cAMPS (Cat. No A 002) with increased lipophilicity and phosphodiesterase stability. The halogen in position 2 of the adenine nucleobase can be used for various sustitutions including spacers and labels. Detailed technical information avalaible. Reference: Gjertsen et al., J. Biol. Chem., 270, 20599 - 20607 (1995).
Cat. No. C 073
CAS number [124844-92-4]
Purity > 99% HPLC
Salt form Sodium
Storage temperature -20°C / -4°F
Molecular formula C₁₀H₁₀ClN₅O₅PS · Na
Molecular weight [g/mol] 401,7
cAMP modified at the exocyclic oxygen equatorial (Rp-)
Modifications 2-cAMP
Target PKA (cAK) Inhibitor
Lipophilicity 1.58
Absorption max [nm] 262
Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] 14300
  • 1. Gjertsen B. T., Mellgren G., Otten A., Maronde E., Genieser H.-G., Jastorff B., Vintermyr O. K., McKnight G. S.Doeskeland S. O., J. Biol. Chem., 270, 20599 - 20607 (1995), "Novel (Rp)-cAMPS Analogs as Tools for Inhibition of cAMP-Kinase in Cell Culture"