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Rp-2'-AHC-cAMPS

2'- O- (6- Aminohexylcarbamoyl)adenosine- 3', 5'- cyclic monophosphorothioate, Rp- isomer ( Rp-2'-AHC-cAMPS )
PDE-resistant Rp-cAMPS functionalized for immobilization or conjugation with markers and dyes
Cat. No.: A 120
    
CAS No.: [pending]
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Product Name Price (net) Qty
Cat. No.: A 120-05
Unit: 5 µmol / ~2.4 mg
$297.00

Analogue of the PKA inhibitor Rp-cAMPS, suitable for immobilization as affinity ligand (e.g. for purification of phosphodiesterases) or for coupling of various labelling structures including fluorophores. PDE-resistant form of 2'-AHC-cAMP (Cat. No. A 046).  Detailed technical information available. Compare: Corrie et al., Prot. Expr. Purif., 3, 417 - 420 (1992).

Cat. No. A 120
CAS number [pending]
Purity > 98% HPLC
Storage temperature -20°C / -4°F
Molecular formula C₁₇H₂₆N₇O₆PS
Molecular weight [g/mol] 487,5
cAMP modified at the exocyclic oxygen equatorial (Rp-)
Modifications 2'-cAMP
Lipophilicity 1.68
Absorption max [nm] 259
Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] 15000
  • 1. Corrie J. E. T., Pizza C., Makwana J.King R. W., Prot. Express. Purif., 3, 417 - 420 (1992), "Preparation and Properties of an Affinity Support for Purification of Cyclic AMP Receptor Protein from Escherichia coli"