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Rp-8-pCPT-cGMPS

8- (4- Chlorophenylthio)guanosine- 3', 5'- cyclic monophosphorothioate, Rp- isomer (Rp-8-pCPT-cGMPS ), sodium salt
Membrane-permeant and PDE-resistant PKG inhibitor
Cat. No.: C 013
    
CAS No.: [153660-04-9]
Shipping: ambient
Product Name Price (net) Qty
Cat. No.: C 013-01
Unit: 1 µmol / ~0.5 mg
$151.00
Specially purified quality, fluorescent impurities removed. For other salt forms please inquire. Potent selective inhibitor of protein kinase G I a, I ß and especially of type II. Activates retinal cGMP channels and thus discriminates between kinase and channel effects. Absolutely resistant against mammalian cyclic nucleotide-dependent phosphodiesterases, no metabolic side effects. Significantly more lipophilic and membrane-permeant compared to Rp-cGMPS or Rp-8-Br-cGMPS. Detailed technical information and updated reference list available on request. References: Butt et al., Eur. J. Pharmacol., 269, 265 - 268 (1994); Gamm et al., J. Biol. Chem., 270, 27380 - 27388 (1996); Kramer et al., J. Neurosci., 16, 1285 - 1293 (1996).
Cat. No. C 013
CAS number [153660-04-9]
Purity > 99% HPLC
Salt form Sodium
Storage temperature -20°C / -4°F
Light-sensitive True
Molecular formula C₁₆H₁₄ClN₅O₆PS₂ · Na
Molecular weight [g/mol] 525.9
Modifications 8-cGMP
Target PKG (cGK) Inhibitor
Lipophilicity 2.61
Absorption max [nm] 276
Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] 21500
  • 1. Beckert U., Grundmann M., Wolter S., Schwede F., Rehmann H., Kaever V., Kostenis E.Seifert R., Biochem. Biophys. Res. Commun., 451, 497 - 502 (2014), "cNMP-AMs Mimic and Dissect Bacterial Nucleotidyl Cyclase Toxin Effects"
  • 2. Jäger R., Russwurm C., Schwede F., Genieser H.-G., Koesling D.Russwurm M., J. Biol. Chem., 287, 1210 - 1219 (2012), "Activation of PDE10 and PDE11 Phosphodiesterases"
  • 3. Heine S., Cote Y. P.Beaudoin A. R., Dissertation, 0, 0 - 0 (2011), "Charakterisierung der Expression und Funktion von zyklisch Nucleotid-gesteuerten Ionenkanälen im nozizeptiven System"
  • 4. Zieba B. J., Artamonov M. V., Jin L., Momotani K., Ho R., Franke A. S., Neppl R. L., Stevenson A. S., Khromov A. S., Chrzanowska-Wodnicka M.Somlyo A. V., J. Biol.Chem., 286, 16681 - 16692 (2011), "The cAMP-Responsive Rap1 Guanine Nucleotide Exchange Factor, Epac, Induces Smooth Muscle Relaxation by Down-regulation of RhoA Activity"
  • 5. Jäger R., Schwede F., Genieser H.-G., Koesling D.Russwurm M., Br. J. Pharmacol., 161, 1645 - 1660 (2010), "Activation of PDE2 and PDE5 cy Specific GAF Ligands: Delayed Activation of PDE5"
  • 6. Paquet-Durand F., Hauck S., Van Veen T., Ueffing M.Ekström P., J. Neurochem., 108, 796 - 810 (2009), "PKG Activity Causes Photoreceptor Cell Death in Two Retinitis pigmentosa Models"
  • 7. Poppe H., Rybalkin S. D., Rehmann H., Hinds T. R., Tang X.-B., Christensen A. E., Schwede F., Genieser H.-G., Bos J. L., Doeskeland S. O., Beavo J. A.Butt E., Nature Methods, 5, 277 - 278 (2008), "Cyclic Nucleotide Analogs as Probes of Signaling Pathways"
  • 8. Song X. J., Wang Z. B., Gan Q.Walters E. T., J. Neurophysiol., 95, 479 - 492 (2006), "cAMP and cGMP Contribute to Sensory Neuron Hyperexcitability and Hyperalgesia in Rats with Dorsal Root Ganglia Compression"
  • 9. Badhwar A., Weston A. D., Murray J. B.Mercier A. J., Peptides, 27, 1281 - 1290 (2006), "A Role for Cyclic Nucleotide Monophosphates in Synaptic Modulation by a Crayfish Neuropeptide"
  • 10. Sung Y. J., Chiu D. T. W.Ambron R. T., Neuroscience, 141, 697 - 709 (2006), "Activation and Retrograde Transport of Protein Kinase G in Rat Nociceptive Neurons After Nerve Injury and Inflammation"
  • 11. Busch C. J., Liu H. L., Graveline A. R.Bloch K. D., Amer. J. Physiol.-Lung Cell. M. Ph., 290, 747 - 753 (2006), "Nitric Oxide Induces Phosphodiesterase 4B Expression in Rat Pulmonary Artery Smooth Muscle Cells"
  • 12. Kim B. J., Lee J. H., Jun J. Y., Chang I. Y., So I.Kim K. W., Mol. Cells, 21, 337 - 342 (2006), "Vasoactive Intestinal Polypeptide Inhibits Pacemaker Activity Via the Nitric Oxide-cGMP-Protein Kinase G Pathway in the Interstitial Cells of Cajal of the Murine Small Intestine"
  • 13. Zhang M. J., Hong H., Zhou B., Jin S., Wang C., Fu M., Wang S.Xia G., J. Endocrinol., 189, 493 - 507 (2006), "The Expression of Atrial Natriuretic Peptide in the Oviduct and its Functions in Pig Spermatozoa"
  • 14. Brown R. L., Strassmaier T., Brady J. D.Karpen J. W., Curr. Pharmaceut. Design, 12, 3597 - 3613 (2006), "The Pharmacology of Cyclic Nucleotide-Gated Channels: Emerging from the Darkness"
  • 15. Li S. J.Sun N. L., Acta Pharmacol. Sin., 26, 323 - 328 (2005), "Regulation of Intracellular Ca2(+) and Calcineurin by NO/PKG in Profileration of Vascular Smooth Muscle Cells"
  • 16. Su J., Scholz P. M.Weiss H. R., Expt. Biol. Med., 230, 242 - 250 (2005), "Differential Effects of cGMP Produced by Soluble and Particulate Guanylyl Cyclase on Mouse Ventricular Myocytes"
  • 17. Leffler C. W., Fedinec A. L., Parfenova H.Jaggar J. H., Amer. J. Physiol.-Heart Circ. Phy., 289, 432 - 438 (2005), "Permissive Contributions of NO and Prostacyclin in CO-induced Cerebrovascular Dilation in Piglets"
  • 18. Li S., Doss J. C., Hardee E. J.Quock R. M., Brain Res., 1038, 113 - 117 (2005), "Involvement of cyclic GMP-dependent Protein Kinase in Nitrous Oxide-induced Anxiolytic-like Behavior in the Mouse Light/Dark Exploration Test"
  • 19. Lohmann S. M.Walter U., Frontiers Biosci., 10, 1313 - 1328 (2005), "Tracking Functions of cGMP-dependent Protein Kinase"
  • 20. Cook A. L. M.Haynes J. M., Cell. Signal., 16, 253 - 261 (2004), "Protein Kinase GII-mediated Proliferative Effects in Human Cultured Prostatic Stromal Cells"
  • 21. Kaminski A., Gao H.Morgan N. G., FEBS Lett., 559, 118 - 124 (2004), "Involvement of the cGMP Signalling Pathway in the Regulation of Viability in Insulin-secreting BRIN-BD11 Cells"
  • 22. Jin X. H., McGrath H. E., Gildea J. J., Siragy H. M., Felder R. A.Carey R. M., Hypertension., 43, 1133 - 1139 (2004), "Renal Interstitial Guanosine Cyclic 3', 5'-monophosphate Mediates Pressure-natriuresis via Protein Kinase G"
  • 23. Gambaryan S., Geiger J., Schwarz U. R., Butt E., Begonja A., Obergfell A.Walter U., Blood, 103, 2593 - 2600 (2004), "Potent Inhibition of Human Platelets by cGMP Analogs Independent of cGMP-dependent Protein Kinase"
  • 24. MacPherson M. R., Lohmann S. M.Davies S. A., J. Biol. Chem., 279, 40026 - 40034 (2004), "Analysis of Drosophila cGMP-dependent Protein Kinases and Assessment of Their in Vivo Roles by Targeted Expression in a Renal Transporting Epithelium"
  • 25. Wu R. Y., Yao K., Flammer J.Haeflinger I. O., Invest. Ophalmol. Vis. Sci., 45, 3231 - 3222 (2004), "Role of Anions in Nitric Oxide-induced Short-circuit Currrent Increase in Isolated Porcine Ciliary Processes"
  • 26. Browner N. C., Sellak H.Lincoln T. M., Am. J. Physiol.-Cell Physiol., 287, 88 - 96 (2004), "Downregulation of cGMP-dependent Protein Kinase Expression by Inflammatory Cytokines in Vascular Smooth-muscle Cells"
  • 27. Etherington S. J.Everett A. W., J.-Physiol., 559, 507 - 517 (2004), "Postsynaptic Production of Nitric Oxide Implicated in Long-term Depression at the Mature Amphibian (Bufo Marinus) Neuromuscular Junction"
  • 28. Li Z., Zhang G., Marjanovic J. A., Ruan C.Du X., J. Biol. Chem., 279, 42469 - 42475 (2004), "A platelet secretion pathway mediated by cGMP-dependent protein kinase"
  • 29. Jensen B. O., Selheim F., Doeskeland S. O., Gear A. R. L.Holmsen H., Blood, 104, 2775 - 2782 (2004), "Protein Kinase A Mediates Inhibition of the Thrombin-Induced Platelet Shape Change by Nitric Oxide"
  • 30. Chen Y., McCarron R. M., Golech S., Bembry J., Ford B., Lenz F. A., Azzam N.Spatz M., Am. J. Physiol.-Cell Physiol., 284, 243 - 249 (2003), "ET-1- and NO-mediated Signal Transduction Pathway in Human Brain Capillary Endothelial Cells"
  • 31. Velardez M. O., Benitez A. H., Cabilla J. P., Bodo C. C. A.Duvilanski B. H., Eur. J. Endocrinol., 148, 89 - 97 (2003), "Nitric Oxide Decreases the Production of Inositol Phosphates Stimulated by Angiotensin II and Thyrotropin-releasing Hormone in Anterior Pituitary Cells"
  • 32. Lee S. Y., Andoh T., Murphy D. L.Chiueh C. C., FASEB J., 17, 411 - 430 (2003), "17 Beta-Estradiol Activates ICI 182,780-sensitive Estrogen Receptors and Cyclic GMP-dependent Thioredoxin Expression for Neuroprotection"
  • 33. Peluso J. J., J. Steroid. Biochem. Mol. Biol., 85, 167 - 173 (2003), "Progesterone as a Regulator of Granulosa Cell Viability"
  • 34. Schmidtko A., Ruth P., Geisslinger G.Tegeder I., Nitric Oxide-Biol. Chem., 8, 89 - 94 (2003), "Inhibition of Cyclic Guanosine 5'-Monophosphate-dependent Protein Kinase 1 (PKG-1) in Lumbar Spinal Cord Reduces Formalin-induced Hyperalgesia and PKG Upregulation"
  • 35. Kook H., Itoh H., Choi B. S., Sawada N., Doi K., Hwang T. J., Kim K. K., Arai H., Baik Y. H.Nakao K., Am. J. Physiol. - Heart Circul. Physiol., 284, 1388 - 1397 (2003), "Physiological Concentration of Atrial Natriuretic Peptide Induces Endothelial Regeneration in Vitro"
  • 36. West G. A., Meno J. R., Nguyen T.-S. K., Ngai A. C., Simard J. M.Winn H. R., J. Cardiovasc. Pharmacol., 41, 444 - 451 (2003), "cGMP-dependent and not cAMP-dependent Kinase is Required for Adenosine-induced Dilation of Intracerebral Arterioles"
  • 37. Brunner F.Wolkart G., Cardiovasc. Res., 60, 355 - 364 (2003), "Peroxynitrite-induced Cardiac Depression: Role of Myofilament Desensitization and cGMP Pathway"
  • 38. Wyatt T. A., Forget M. A.Sisson J. H., Am. J. Pathol., 163, 1157 - 1166 (2003), "Ethanol stimulates Ciliary Beating by Dual Cyclic Nucleotide Kinase Activation in Bovine Bronchial Epithelial Cells"
  • 39. Jernigan N. L., Walker B. R.Resta T. C., Am. J. Physiol.-Lung Cell. Mol. Physiol., 285, 634 - 642 (2003), "Pulmonary PKG-1 is Upregulated Following Chronic Hypoxia"
  • 40. Li Z. Y., Ajdic J., Eigenthaler M.Du X. P., Blood., 101, 4423 - 4429 (2003), "A Predominat Role for cAMP-dependent Protein Kinase in the cGMP-induced Phosphorylation of Vasodilator-stimulated Phosphorprotein and Platelet Inhibition in Humans"
  • 41. Sengenes C., Bouloumie A., Hauner H., Berlan M., Busse R., Lafontan M.Galitzky J., J. Biol. Chem., 278, 48617 - 48626 (2003), "Involvement of a cGMP-dependent Pathway in the Natriuretic Peptide-mediated Hormone-sensitive Lipase Phosphorylation in Human Adipocytes"
  • 42. Kiemer A. K., Bildner N., Weber N. C.Vollmar A. M., Endocrinology, 144, 802 - 812 (2003), "Characterization of Heme Oxygenase 1 (Heat Shock Protein 32) Induction by Atrial Natriuretic Peptide in Human Endothelial Cells"
  • 43. Gainey L. F.Greenberg M. J., J. Exp. Biol., 206, 3507 - 3520 (2003), "Nitric Oxide Mediates Seasonal Muscle Potentation in Clam Gills"
  • 44. Payne C. M., Waltmire C. N., Crowley C., Crowley-Weber C. L., Dvorakova K., Bernstein H., Bernstein C., Holubec H.Garewal H., Cell Biol. Toxicol., 19, 373 - 392 (2003), "Caspase-6 Mediated Cleavage of Guanylate Cyclase Alpha I During Deoxycholate Apoptosis: Protective Role of the Nitric Oxide Signaling Module [Review]"
  • 45. Gambaryan S., Butt E., Marcus K., Glazova M., Palmetshofer A., Guillon G.Smolenski A., J. Biol. Chem., 278, 29640 - 29648 (2003), "cGMP-dependent Protein Kinase Type II Regulates Basal Level of Aldosterone Production by Zona Glomerulosa Cells Without Increasing Expression of the Steroidgenic Acute Regulatory Protein Gene"
  • 46. Wang S., Shiva S., Poczatek M. H., Darley-Usmar V.Murphy-Ullrich J. E., J. Biol. Chem., 277, 9880 - 9888 (2002), "Nitric Oxide and cGMP-dependent Protein Kinase Regulation of Glucose-mediated Thrombospondin 1-dependent Transforming Growth Factor-Beta Activation in Mesangial Cells"
  • 47. Silva J. M.Lewis D. L., Pflugers Arch., 443, 671 - 675 (2002), "Nitric Oxide Enhances Ca2+-dependent K+ Channel Activity in Rat Carotid Body Cells"
  • 48. Wang J. P., Chang L.-C., Raung S.-L., Hsu M.-F., Huang L.-J.Kuo S.-C., Biochem. Pharmacol., 63, 577 - 585 (2002), "Inhibition of Superoxide Anion Generation by YC-1 in Rat Neutrophils through Cyclic GMP-dependent and -independent Mechanisms"
  • 49. Guedes D. N., Barbosa J. M., Lemos V. S.Cortes S. F., J. Pharm. Pharmacol., 54, 853 - 858 (2002), "Mechanism of the Vasodilator Effect of 12-O-Methylcurine in Rat Aortic Rings"
  • 50. Friis U. G., Jensen B. L., Sethi S., Andreasen D., Hansen P. B.Skott O., Circ. Res., 90, 996 - 1003 (2002), "Control of Renin Secretion from Rat Juxtaglomerular Cells by cAMP-specific Phosphodiesterases"
  • 51. Begum N., Sandu O. A.Duddy N., Diabetes, 51, 2256 - 2263 (2002), "Negative Regulation of Rho Signaling by Insulin and its Impact on Actin Cytoskeleton Organization in Vascular Smooth Muscle Cells - Role of Nitric Oxide and Cyclic Guanosine Monophosphate Signaling Pathways"
  • 52. Shimoda L. A., Welsh L. E.Pearse D. B., Am. J. Physiol.-Lung Cell. Mol. Physiol., 283, 297 - 304 (2002), "Inhibition of Inwardly Rectifying K+ Channels by cGMP in Pulmonary Vascular Endothelial Cells"
  • 53. Han J., Kim N., Joo H., Kim E.Earm Y. E., Am. J. Physiol. - Heart Circul. Physiol., 283, 1545 - 1554 (2002), "ATP-Sensitive K+ Channel Activation by Nitric Oxide and Protein Kinase G in Rabbit Ventricular Myocytes"
  • 54. Filipeanu C. M., Brailoiu E., Le Dun S.Dun N. J., J. Neurochem., 83, 879 - 884 (2002), "Urotensin-II Regulates Intracellular Calcium in Dissociated Rat Spinal Cord Neurons"
  • 55. D'Ascenzo M., Martinotti G., Azzena G. B.Grassi G., J. Neurosci., 22, 7485 - 7492 (2002), "cGMP/Protein Kinase G-dependent Inhibition of N-Type Ca2+ Channels Induced by Nitric Oxide in Human Neuroblastoma IMR32 Cells"
  • 56. Hassock S., Zhu M. X., Trost C., Flockerzi V.Authi K. S., Blood, 100, 2801 - 2811 (2002), "Expression and role of TRPC Proteins in Human Platelets: Evidence that TRPC6 Forms the Store-independent Calcium Entry Channel"
  • 57. Zhu S., Han G.White R. E., J. Vasc. Res., 39, 477 - 488 (2002), "PGE(2) Action in Human Coronary Artery Smooth Muscle: Role of Potassium Channels and Signaling Cross-Talk"
  • 58. Wang J. P., Chang L.-C., Huang L.-J.Kuo S.-C., Biochem. Pharmacol., 62, 679 - 684 (2001), "Inhibition of Extracellular Ca2+ Entry by YC-1, an Activator of Soluble Guanylyl Cyclase, through a Cyclic GMP-independent Pathway in Rat Neutrophils"
  • 59. Spicuzza L., Belvisi M. G., Birrell M. A., Barnes P. J., Hele D. J.Giembycz M. A., Br. J. Pharmacol., 133, 1201 - 1212 (2001), "Evidence that the Anti-Spasmogenic Effect of the Beta-Adrenoceptor Agonist, Isoprenaline, on Guinea-Pig Trachealis is not Mediated by Cyclic AMP-dependent Protein Kinase"
  • 60. Sando O. A., Ito M.Begum N., J. Appl. Physiol., 91, 1475 - 1482 (2001), "Signal Transduction in Smooth Muscle - Selected Contribution: Insulin Utilizes NO/cGMP Pathway to Activate Myosin Phosphatase via Rho Inhibition in Vascular Smooth Muscle"
  • 61. Gao Y. S.Raj J. U., Eur. J. Pharmacol., 418, 111 - 116 (2001), "SQ22536 and W-7 Inhibit Forskolin-induced cAMP Elevation but not Relaxation in Newborn Ovine Pulmonary Veins"
  • 62. Revelli A., Costamagna C., Moffa F., Aldieri E., Ochetti S., Bosia A., Massobrio M., Lindblom B.Ghigo D., Biol. Reprod., 64, 1708 - 1712 (2001), "Signaling Pathway of Nitric Oxide-induced Acrosome Reaction in Human Spermatozoa"
  • 63. Osinski M. T., Rauch B. H.Schrör K., Mol. Pharmacol., 59, 1044 - 1050 (2001), "Antimitogenic Actions of Organic Nitrates are Potentiated by Sildenafil and Mediated via Activation of Protein Kinase A"
  • 64. Abi-Gerges N., Fischmeister R.Mery P. F., J. Physiol.-London, 531, 117 - 130 (2001), "G Protein-mediated Inhibitory Effect of a Nitric Oxide Donor on the L-Type Ca2+ Current in Rat Ventricular Myocytes"
  • 65. Thompson W. J.Pamukcu R., 11th Intl. Conference on Second Messengers and Phosphoproteins Melbourne Australia, 0, 0 - 0 (2001), "Cyclic GMP-dependent Protein Kinase Activation by Exisulind and Analogs to Induce Apoptosis in Colon Tumor Cells Involves Inhibition of Cylic GMP Phosphodiesterase(s)"
  • 66. Zhu Y. K., Liu X. D., Sköld M. C., Umino T., Wang H. J., Romberger D. J., Spurzem J. R., Kohyama T., Wen F.-Q.Rennard S. I., Am. J. Respir. Cell. Mol. Biol., 25, 245 - 253 (2001), "Cytokine Inhibition of Fibroblast-induced Gel Contraction is Mediated by PGE(2) and NO Acting through Separate Parallel Pathways"
  • 67. Staples K. J., Bergmann M., Tomita K., Houslay M. D., McPhee I., Barnes P. J., Giembycz M. A.Newton R., J. Immunol., 167, 2074 - 2080 (2001), "Adenosine 3', 5'-cyclic Monophosphate (cAMP)-dependent Inhibition of IL-5 from Human T Lymphocytes is not Mediated by the cAMP-dependent Protein Kinase A(1)"
  • 68. Pawliczak R., Cowan M. J., Huang X. L., Nanavaty U. B., Alsaaty S., Logun C.Shelhamer J. H., J. Biol. Chem., 276, 44613 - 44621 (2001), "p11 Expression in Human Bronchial Epithelial Cells is Increased by Nitric Oxide in a cGMP-dependent Pathway Involving Protein Kinase G Activation"
  • 69. Jin X. H., Siragy H. M.Carey R. M., Hypertension, 38, 309 - 316 (2001), "Renal Interstitial cGMP Mediates Natriuresis by Direct Tubule Mechanism"
  • 70. Nauli S. M., Williams J. M.Pearce W. J., Dev. Neurosci., 23, 224 - 233 (2001), "Effects of Maturation on Mechanisms of cGMP-induced Cerebral Vasodilatation"
  • 71. Lawrence D. W.Pryzwansky K. B., J. Immunol., 166, 5550 - 5556 (2001), "The Vasodilator-stimulated Phosphoprotein is Regulated by Cyclic GMP-dependent Protein Kinase During Neutrophil Spreading"
  • 72. Hou L. F.Wang X., J. Neurosci. Res., 66, 592 - 600 (2001), "PKC and PKA, but not PKG Mediate LPS-induced CGRP Release and [Ca2+](i) Elevation in DRG Neurons of Neonatal Rats"
  • 73. Bader B., Butt E., Palmetshofer A., Walter U., Jarchau T.Drueckes P., J. Biomol. Screen., 6, 255 - 264 (2001), "A cGMP-dependent Protein Kinase Assay for High Throughput Screening Based on Time-Resolved Fluorescence Resonance Energy Transfer"
  • 74. Tao Y.Johns R. A., United States Patent Application: 0010031750, 0, 0 - 0 (2001), "Isoform Specific Inhibition for Treatment of Pain and Reduction of Anesthetic Treshold"
  • 75. Tao Y. X., Hassan A., Haddad E.Johns R. A., Neuroscience, 95, 525 - 533 (2000), "Expression and Action of Cyclic GMP-Dependent Protein Kinase I Alpha in Inflammatory Hyperalgesia in Rat Spinal Cord"
  • 76. Tao Y. X., Hassan A.Johns R. A., Anesthesiology, 92, 493 - 499 (2000), "Intrathecally Administered cGMP-Dependent Protein Kinase I Alpha Inhibitor Significantly Reduced the Threshold for Isoflurane Anesthesia - Implication for a Novel Role of cGMP-Dependent Protein Kinase I Alpha"
  • 77. Mitani Y., Zaidi S. H. E., Dufourcq P., Thompson K.Rabinovitch M., FASEB J., 14, 805 - 814 (2000), "Nitric Oxide Reduces Vascular Smooth Muscle Cell Elastase Activity through cGMP-Mediated Suppression of ERK Phosphorylation and AML1B Nuclear Partitioning"
  • 78. Tao Y. X.Johns R. A., Eur. J. Pharmacol., 392, 141 - 145 (2000), "Activation of cGMP-Dependent Protein Kinase I Alpha is Required for N-Methyl-D-Aspartate- or Nitric Oxide-Produced Spinal Thermal Hyperalgesia"
  • 79. White R. E., Kryman J. P., El-Mowafy A. M., Han G. C.Carrier G. O., Circ. Res., 86, 897 - 905 (2000), "cAMP-Dependent Vasodilators Cross-Activate the cGMP-Dependent Protein Kinase to Stimulate BKCa Channel Activity in Coronary Artery Smooth Muscle Cells"
  • 80. Scott S.-P., Cummings J., Joe J. C.Tanaka J. C., Biophys. J., 78, 2321 - 2333 (2000), "Mutating Three Residues in the Bovine Rod Cyclic Nucleotide-Activated Channel Can Switch a Nucleotide from Inactive to Active"
  • 81. Sirotkin A. V., Makarevich A. V., Genieser H.-G., Kotwica J.Hetenyi L., Exp. Clin. Endocrinol. Diabetes, 108, 214 - 219 (2000), "Effect of four cGMP Analogues with Different Mechanisms of Action on Hormone Release by Porcine Ovarian Granulosa Cells In Vitro"
  • 82. Parra J., Cantabrana B.Hidalgo A., Life Sci., 66, 2563 - 2569 (2000), "Mechanism of Mifepristone-Induced Spasmolytic Effect on Isolated Rat Uterus"
  • 83. Fukai T., Siegfried M. R., Ushio-Fukai M., Cheng Y., Kojda G.Harrison D. G., J. Clin. Invest., 105, 1631 - 1639 (2000), "Regulation of the Vascular Extracellular Superoxide Dismutase by Nitric Oxide and Exercise Training"
  • 84. Johansson C., Aandahl E. M., Aukrust P., Müller F., Hansson V., Froeland S. S.Tasken K., 12th Protein Kinase Symp. NO/cGMP and Protein Kinase Signaling Bad Brückenau/Germany, 0, 0 - 0 (2000), "Protein Kinase A Type I Antagonist as an Immune-Modulating Therapy"
  • 85. Velardez M. O., De Laurentiis A., Diaz M. D., Lasaga M., Pisera D., Seilicovich A.Duvilanski B. H., Eur. J. Endocrinol., 143, 279 - 284 (2000), "Role of Phosphodiesterase and Protein Kinase G on Nitric Oxide-Induced Inhibition of Prolactin Release from the Rat Anterior Pituitary"
  • 86. Schwede F., Maronde E., Genieser H.-G.Jastorff B., Pharmacol. Ther., 87, 199 - 226 (2000), "Cyclic Nucleotide Analogs as Biochemical Tools and Prospective Drugs"
  • 87. Musialek P., Rigg L., Terrar D. A., Paterson D. J.Casadei B., J. Mol. Cell. Cardiol., 32, 1831 - 1840 (2000), "Role of cGMP-inhibited Phosphodiesterase and Sarcoplasmic Calcium in Mediating the Increase in Basal Heart Rate with Nitric Oxide Donors"
  • 88. Ellis D. Z., Nathanson J. A.Sweadner K. J., Am. J. Physiol.-Cell Physiol., 279, 1685 - 1693 (2000), "Carbachol Inhibits Na+-K+-ATPase Activity in Choroid Plexus via Stimulation of the NO/cGMP Pathway"
  • 89. Sirotkin A. V., Makarevich A. V., Pivko J., Kotwica J., Genieser H.-G.Bulla J., J. Steroid Biochem. Mol. Biol., 74, 1 - 9 (2000), "Effect of cGMP Analogues and Protein Kinase G Blocker on Secretory Activity, Apoptosis and the cAMP/Protein Kinase A System in Porcine Ovarian Granulosa Cells In Vitro"
  • 90. Ferrero R., Rodriguez-Pascual F., Miras-Portugal M. T.Torres M., J. Neurochem., 75, 2029 - 2039 (2000), "Nitric Oxide-Sensitive Guanylyl Cyclase Activity Inhibition through Cyclic GMP-Dependent Dephosphorylation"
  • 91. Osinski M., Ph.D. Thesis Düsseldorf/Germany, 0, 0 - 0 (2000), "Pharmakologische Ansätze einer Proteinkinase A-Aktivierung zur Hemmung der Mitogenese glatter Gefäßmuskelzellen"
  • 92. Polleux F., Morrow T.Ghosh A., Nature, 404, 567 - 573 (2000), "Semaphorin 3A is a chemoattractant for cortical apical dendrites"
  • 93. Lewin M. R.Walters E. T., Nature Neurosci., 2, 18 - 23 (1999), "Cyclic GMP Pathway is critical for Inducing Long-term Sensitization of Nociceptive Sensory Neurons"
  • 94. Sequeira S. M., Carvalho A. P.Carvalho C. M., Neurosci. Lett., 261, 29 - 32 (1999), "Both Protein Kinase G Dependent and Independent Mechanisms are Involved in the Modulation of Glutamate Release by Nitric Oxide in Rat Hippocampal Nerve Terminals"
  • 95. Reyes-Harde M., Empson R., Potter B. V. L., Galione A.Stanton P. K., Proc. Natl. Acad. Sci. USA, 96, 4061 - 4066 (1999), "Evidence of a Role for Cyclic ADP-Ribose in Long-term Synaptic Depression in Hippocampus"
  • 96. Yawo H., J. Neurosci., 19, 5293 - 5300 (1999), "Involvement of cGMP-Dependent Protein Kinase in Adrenergic Potentiation of Transmitter Release from the Calyx-Type Presynaptic Terminal"
  • 97. Rodriguez-Pascual F., Ferrero R., Miras-Portugal M. T.Torres M., Arch. Biochem. Biophys., 366, 207 - 214 (1999), "Phosphorylation of Tyrosine Hydroxylase by cGMP-Dependent Protein Kinase in Intact Bovine Chromaffin Cells"
  • 98. Maronde E., Wicht H., Tasken K., Genieser H.-G., Dehghani F., Olcese J.Korf H.-W., J. Pineal Res., 27, 170 - 182 (1999), "CREB Phosphorylation and Melatonin Biosynthesis in the Rat Pineal Gland: Involvement of cyclic AMP-dependent Protein KinaseType II"
  • 99. Tao J. C., Mallat A., Gallois C., Belmadani S., Mery P.-F., Tran-Van Nhieu J., Pavoine C.Lotersztajn S., J. Biol. Chem., 274, 23761 - 23769 (1999), "Biological Effects of C-Type Natriuretic Peptide in Human Myofibroblastic Hepatic Stellate Cells"
  • 100. Fernandez-Tome P., Lizasoain I., Leza J. C., Lorenzo P.Moro M. A., Neuropharmacology, 38, 1307 - 1315 (1999), "Neuroprotective Effects of DETA-NONOate, a Nitric Oxide Donor, on Hydrogen Peroxide-Induced Neurotoxicity in Cortical Neurones"
  • 101. Ashur-Fabian O., Perl O., Lilling G., Fridkin M.Gozes I., Peptides, 20, 629 - 633 (1999), "SNV, a Lipophilic Superactive VIP Analog, Acts through cGMP to Promote Neuronal Survival"
  • 102. Gray D. B., Polo-Parada L., Pilar G. R., Eang P., Metzger R. R., Klann E.Meriney S. D., J. Neurochem., 72, 1981 - 1990 (1999), "A Nitric Oxide/Cyclic GMP-Dependent Protein Kinase Pathway Alters Transmitter Release and Inhibition by Somatostatin at a Site Downstream of Calcium Entry"
  • 103. Straznicka M., Gong G., Yan L., Scholz P. M.Weiss H. R., J. Cardiovasc. Pharmacol., 34, 229 - 236 (1999), "Cyclic GMP Protein Kinase Mediates Negative Metabolic and Functional Effects of Cyclic GMP in Control and Hypertrophied Rabbit Cardiac Myocytes"
  • 104. Ho A. K., Hashimoto K.Chik C. L., J. Neurochem., 73, 598 - 604 (1999), "3', 5'-Cyclic Guanosine Monophosphate Activates Mitogen-Activated Protein Kinase in Rat Pinealocytes"
  • 105. Reyes-Harde M., Potter B. V. L., Galione A.Stanton P. K., J. Neurophysiol., 82, 1569 - 1576 (1999), "Induction of Hippocampal LTD Requires Nitric-Oxide-Stimulated PKG Activity and Ca2+ Release from Cyclic ADP-Ribose-Sensitive Stores"
  • 106. Szönyi M., He D. Z. Z., Ribari O., Sziklai I.Dallos P., Hear. Res., 137, 29 - 42 (1999), "Cyclic GMP and outer Hair Cell Electromotility"
  • 107. Sisson J. H., May K.Wyatt T. A., Alcohol. Clin. Exp. Res., 23, 1528 - 1533 (1999), "Nitric Oxide-Dependent Ethanol Stimulation of Ciliary Motility is Linked to cAMP-Dependent Protein Kinase (PKA) Activation in Bovine Bronchial Epithelium"
  • 108. Ropero A. B., Fuentes E., Rovira J. M., Ripoll C., Soria B.Nadal A., J. Physiol., 521, 397 - 407 (1999), "Non-Genomic Actions of 17Beta-Oestradiol in Mouse Pancreatic Beta-Cells are Mediated by a cGMP-Dependent Protein Kinase"
  • 109. Francis S. H.Corbin J. D., Crit. Rev. Clin. Lab. Sci., 36, 275 - 328 (1999), "Cyclic Nucleotide-Dependent Protein Kinases: Intracellular Receptors for cAMP and cGMP Action"
  • 110. Pfeifer A., Ruth P., Dostmann W., Sausbier M., Klatt P.Hofmann F., in Rev. Physiol. Biochem. Pharmacol. Berlin / Springer, 135, 105 - 149 (1999), "Structure and Function of cGMP-Dependent Protein Kinases"
  • 111. Sirotkin A., Makarevic A., Kotwica J., Genieser H.-G.Bulla J., J. Farm. Animal. Sci., 32, 11 - 14 (1999), "Effect of Chemical Analogues of cAMP and cGMP on Hormone and Growth Factor Secretion by Porcine Ovarian Cells"
  • 112. Wei J.-Y., Cohen E. D., Genieser H.-G.Barnstable C. J., J. Mol. Neurosci., 10, 53 - 64 (1998), "Substituted cGMP Analogs Can Act as Selective Agonists of the Rod Photoreceptor cGMP-Gated Cation Channel"
  • 113. Kurtz A., Götz K.-H., Hamann M., Kieninger M.Wagner C., Amer. J. Physiol., 43, 709 - 717 (1998), "Stimulation of Renin Secretion by NO Donors is Related to the cAMP Pathway"
  • 114. Schwarz P. M., Rodriguez-Pascual F., Koesling D., Torres M.Forstermann U., Neuroscience, 82, 255 - 265 (1998), "Fuctional Coupling of Nitric Oxide Synthase And Soluble Guanylyl Cyclase In Controlling Catecholamine Secretion From Bovine Chromaffin Cells."
  • 115. Smolenski A., Burkhardt A. M., Eigenthaler M., Butt E., Gambaryan S., Lohmann S. M.Walter U., Naunyn-Schmied. Arch. Pharmacol., 358, 134 - 139 (1998), "Functional Analysis of cGMP-dependent Protein Kinases I and II as Mediators of NO/cGMP Effects"
  • 116. Begum N., Ragolia L., Rienzie J., McCarthy M.Duddy N., J. Biol. Chem., 273, 25164 - 25170 (1998), "Regulation of Mitogen-activated Protein Kinase Phosphatase-1 Induction by Insulin in Vascular Smooth Muscle Cells"
  • 117. Hood J.Granger H. J., J. Biol. Chem., 273, 23504 - 23508 (1998), "Protein Kinase G Mediates Vascular Endothelial Growth Factor-induced Raf-1 Activation and Proliferation in Human Endothelial Cells"
  • 118. Waniishi Y., Inoue R., Morita H., Teramoto N., Abe K.Ito Y., J. Physiol., 511, 719 - 731 (1998), "Cyclic GMP-dependent but G-Kinase-independent Inhibition of Ca2+-dependent Cl-currents by NO Donors in Cat Tracheal Smooth Muscle"
  • 119. Wyatt T. A., Spurzem J. R., May K.Sisson J. H., Amer. J. Physiol.- Lung Cell Mol. Physiol., 19, 827 - 835 (1998), "Regulation of Ciliary Beat Frequency by both PKA and PKG in Bovine Airway Epithelial Cells"
  • 120. Firestein B. L.Bredt D. S., J. Neurochem., 71, 1846 - 1853 (1998), "Regulation of Sensory Neuron Precursor Proliferation by Cyclic GMP-Dependent Protein Kinase"
  • 121. Lee S.-J., Madden P. J.Shen S. S., Exp. Cell Res., 242, 328 - 340 (1998), "U73122 Blocked the cGMP-Induced Calcium Release in Sea Urchin Eggs"
  • 122. Han J., Kim E., Lee S. H., Yoo S., Ho W.-K.Earm Y. E., Pflugers Arch.-Eur. J. Physiol., 435, 388 - 393 (1998), "cGMP Facilitates Calcium Current via cGMP-Dependent Protein Kinase in Isolated Rabbit Ventricular Myocytes"
  • 123. Fouty B., Komalavilas P., Muramatsu M., Cohen A., McMurtry I. F., Lincoln T. M.Rodman D. M., Amer. J. Physiol.-Heart Circ. Physiol., 43, 672 - 678 (1998), "Protein Kinase G is not Essential to NO-cGMP Modulation of Basal Tone in Rat Pulmonary Circulation"
  • 124. Elferink J. G. R.de Koster B. M., Immunopharmacology, 38, 229 - 236 (1998), "N-Acetylcysteine Causes a Transient Stimulation of Neutrophil Migration"
  • 125. Gambaryan S., Wagner C., Smolenski A., Walter U., Poller W., Haase W., Knutz A.Lohmann S. M., PNAS, 95, 9003 - 9008 (1998), "Endogenous or Overexpressed cGMP-dependent Renin Release from Rat Isolated Perfused Kidney, Microdissected Glomeruli, and Isolated Juxtaglomerular Cells"
  • 126. Vaandrager A. B., Bot A. G. M.De Jonge H. R., Gastroenterology, 112, 437 - 443 (1997), "Guanosine 3',5'-Cyclic Monophosphate-Dependent Protein Kinase II Mediates Heat-Stable Enterotoxin-Provoked Chloride Secretion in Rat Intestine"
  • 127. Hölschermann H., Noll T., Hempel A.Piper H. M., Amer. J. Physiol.-Heart Circul. Physiol., 41, 91 - 98 (1997), "Dual Role of cGMP in Modulation of Macromolecule Permeability of Aortic Endothelial Cells"
  • 128. Tolloczko B., Jia Y. L.Martin J. G., Amer. J. Physiol., 16, 865 - 871 (1997), "Effects of cAMP on Serotonin Evoked Calcium Transients in Cultured Rat Airway Smooth Muscle Cells"
  • 129. Vaandrager A. B., Edixhoven M., Bot A. G. M., Kroos M. A., Jarchau T., Lohmann S. M., Genieser H.-G.De Jonge H. R., J. Biol. Chem., 272, 11816 - 11823 (1997), "Endogenous Type II cGMP-Dependent Protein Kinase Exists as a Dimer in Membranes and can be Functionally Distinguished from the Type I Isoforms"
  • 130. Craven P. A., Studer R. K., Felder J., Phillips S.Derubertis F. R., Diabetes, 46, 671 - 81 (1997), "Nitric Oxide Inhibition of Transforming Growth Factor-Beta and Collagen Synthesis in Mesangial Cells"
  • 131. Bonkale W. L., Cowburn R. F., Winblad B.Fastbom J., Brain Res., 763, 1 - 13 (1997), "Autoradiographic Characterization of (H-3)cGMP Binding Sites in the Rat Brain."
  • 132. Elferink J. G. R., Daha M. R.de Koster B. M., Cell. Mol. Life Sci., 53, 593 - 599 (1997), "A Cyclic GMP- and G-kinase-dependent Effect of Azathioprine on Migration by Human Neutrophils"
  • 133. Xu X., Zeng W. Z., Diaz J., Lau K. S., Gukovskaya A. C., Brown R. J., Pandol S. J.Muallem S., Cell Calcium, 22, 217 - 28 (1997), "NNOS and CA2+ Influx in Rat Pacreatic Acinar and Submandibular Salivary Gland Cells"
  • 134. Lemos V. S., Bucher B., Cortes S. F.Takeda K., Eur. J. Neurosci., 9, 1144 - 1152 (1997), "Inhibition of [Ca2+]i Transients in Rat Adrenal Chromaffin Cells by Neuropeptide Y: Role for a cGMP-dependent Protein Kinase-activated K+ Conductance"
  • 135. Wanikiat P., Woodward D. F.Armstrong R. A., Br. J. Pharmacol., 122, 1135 - 1145 (1997), "Investigation of the Role of Nitric Oxide and Cyclic GMP in Both the Activation and Inhibition of Human Neutrophils"
  • 136. Takeuchi T., Fujita A., Nishio H.Hata F., J. Smooth Muscle Res., 33, 163 - 174 (1997), "Essential Role of Newly Synthesized ATP for Cyclic GMP-induced Relaxation in Alpha-Toxin Permeabilized Smooth Muscle of Rat Proximal Colon"
  • 137. Dixon D. B.Copenhagen D. R., J. Neurosci., 17, 8945 - 8954 (1997), "Metabotropic Glutamate Receptor-Mediated Suppression of an Inward Rectifier Current is Linked via a cGMP Cascade"
  • 138. Van Uffelen B. E., van Steveninck J.Elferink J. G. R., Immunopharmacology, 37, 257 - 267 (1997), "Potentiation and Inhibition of FMLP-Activated Exocytosis in Neutrophils by Exogenous Nitric Oxide"
  • 139. Elferink J. G. R., Daha M. R.de Koster B. M., Inflammation, 21, 93 - 103 (1997), "The Effect of Sodium Aurothiomalate on Stimulated and Non-Stimulated Migration by Human Neutrophils: The Role of Cyclic GMP"
  • 140. Syrovets T., Tippler B., Rieks M.Simmet T., Blood, 89, 4574 - 4583 (1997), "Plasmin is a Potent and Specific Chemoattractant for Human Peripheral Monocytes Acting via a Cyclic Guanosine Monophosphate-Dependent Pathway"
  • 141. Lohmann S. M., Vaandrager A. B., Smolenski A., Walter U.De Jonge H. R., Trends Biochem. Sci., 22, 307 - 312 (1997), "Distinct and Specific Functions of cGMP-Dependent Protein Kinases"
  • 142. Brent P. J., Herd L., Saunders H., Sim A. T. R.Dunkley P. R., J. Neurochem., 68, 2201 - 2211 (1997), "Protein Phosphorylation and Calcium Uptake into Rat Forebrain Synaptosomes: Modulation by the o Ligand, 1,3-Ditolylguanidine"
  • 143. Van Uffelen B. E., de Koster B. M., van den Broek P. J. A., van Steveninck J.Elferink J. G. R., J. Leucocyte Biol., 60, 94 - 100 (1996), "Modulation of Neutrophil Migration by Exogenous Gaseous Nitric Oxide"
  • 144. Van Uffelen B. E., de Koster B. M., van Steveninck J.Elferink J. G. R., Biochem. Biophys. Res. Commun., 226, 21 - 26 (1996), "Carbon Monoxide Enhances Human Neutrophil Migration in a Cyclic GMP-dependent Way"
  • 145. Hichami A., Boichot E., Germain N., Coqueret O.Lagente V., Life Sci., 59, 255 - 261 (1996), "Interactions Between cAMP- and cGMP-dependent Protein Kinase Inhibitors and Phosphodiesterase IV Inhibitors on Arachidonate Release from Human Monocytes"
  • 146. Kramer R. H.Tibbs G. R., J. Neurosci., 16, 1285 - 1293 (1996), "Antagonists of Cyclic Nucleotide-gated Channels and Molecular Mapping of their Site of Action"
  • 147. Willmott N., Sethi J. K., Walseth T. F., Lee H. C., White A. M.Galione A., J. Biol. Chem., 271, 3699 - 3705 (1996), "Nitric Oxide-induced Mobilization of Intracellular Calcium Via the Cyclic ADP-ribose Signaling Pathway"
  • 148. Mathes C.Thompson S. H., J. Neurosci., 16, 1702 - 1709 (1996), "The Nitric Oxide/cGMP Pathway Couples Muscarinic Receptors to the Activation of Ca2+ Influx"
  • 149. Wang Y.Telfer W. H., Insect Biochem. Molec. Biol., 26, 85 - 94 (1996), "Cyclic Nucleotide-induced Termination of Vitellogenin Uptake by Hyalophora cecropia Follicles"
  • 150. Gamm D. M., Francis S. H., Angelotti T. P., Corbin J. D.Uhler M. D., J. Biol. Chem., 270, 27380 - 27388 (1996), "The Type II Isoform of cGMP-dependent Protein Kinase is Dimeric and Possesses Regulatory and Catalytic Properties Distinct from the Type I Isoforms"
  • 151. Pilar G., Gray D. B.Meriney S. D., Life Sci., 58, 1979 - 1986 (1996), "Membrane Delimited and Intracellular Soluble Pathways in the Somatostatin Modulation of ACH Release"
  • 152. Kroner C., Boekhoff I., Lohmann S. M., Genieser H.-G.Breer H., Eur. J. Biochem., 236, 632 - 637 (1996), "Regulation of Olfactory Signalling Via cGMP-dependent Protein Kinase"
  • 153. Yamakage M., Hirshman C. A.Croxton T. L., Am. J. Physiol., 14, 338 - 345 (1996), "Sodium Nitroprusside Stimulates Ca2+activated K+ Channels in Porcine Tracheal Smooth Muscle Cells"
  • 154. Mothet J.-P., Fossier P., Tauc L.Baux G., Proc. Natl. Acad. Sci. USA, 93, 8721 - 8726 (1996), "Opposite Actions of Nitric Oxide on Cholinergic Synapses: Which Pathways?"
  • 155. Studer R. K., De Rubertis F. R.Craven P. A., J. Amer. Soc. Nephrol., 7, 999 - 1005 (1996), "Nitric Oxide Suppresses Increases in Mesangial Cell Protein Kinase C, Transforming Growth Factor Beta and Fibronectin Synthesis Induced by Thromboxane"
  • 156. Guihard G., Combettes L.Capiod T., Biochem. J., 318, 849 - 855 (1996), "3':5'-Cyclic Guanosine Monophosphate (cGMP) Potentiates the Inositol 1,4,5-Trisphosphate- evoked Ca2+ Release in Guinea-pig Hepatocytes"
  • 157. Jorgensen T. D., Dissing S.Gromada J., FEBS Lett., 391, 117 - 120 (1996), "Cyclic GMP Potentiates Phenylephrine but not Cyclic ADP-ribose-evoked Calcium Release from Rat Lacrimal Acinar Cells"
  • 158. Rodriguez-Pascual F., Miras-Portugal M. T.Torres M., Mol. Pharmacol., 49, 1058 - 1070 (1996), "Effect of Cyclic GMP-increasing Agents Nitric Oxide and C-type Natriuretic Peptide on Bovine Chromaffin Cell Function: Inhibitory Role Mediated by Cyclic GMP-dependent Protein Kinase"
  • 159. Azula F. J., Alzola E. S., Conde M., Trueba M., Macarulla J. M.Marino A., Mol. Pharmacol., 50, 367 - 379 (1996), "Thrombin-stimulated Phospholipase C Activity is Inhibited Without Visible Delay by a Rapid Increase in the Cyclic GMP Levels Induced by Sodium Nitroprusside"
  • 160. Abdalla S., Müller-Esterl W.Quitterer U., Eur. J. Biochem., 241, 498 - 506 (1996), "Two Distinct Ca2+ Influx Pathways Activated by the Bradykinin B2 Receptor"
  • 161. Sadighi Akha A. A., Willmott N. J., Brickley K., Dolphin A. C., Galione A.Hunt S. V., J. Biol. Chem., 271, 7297 - 7300 (1996), "Anti-Ig-induced Calcium Influx in Rat B Lymphocytes Mediated by cGMP Through a Dihydropyridine-sensitive Channel"
  • 162. Hemmings H. C., in Regulatory Protein Modification: Techniques and Protocols H.C. Hemmings (ed.) Humana Press Inc., 0, 121 - 218 (1996), "Protein Kinase and Phosphatase Inhibitors. Applications in Neuroscience"
  • 163. Stief C. G., Ückert S., Truss M. C., Becker A. J., Machtens S.Jonas U., Urolog. Res., 24, 333 - 337 (1996), "A Possible Role for Nitric Oxide in the Regulation of Human Uretral Smooth Muscle Tone In Vitro"
  • 164. Hichami A., Boichot E., Germain N., Berdyshev E., Coqueret O.Lagente V., Mediat. Inflamm., 5, 425 - 428 (1996), "Phosphodiesterase 4 Inhibitors and DB-cAMP Inhibit TNF-Alpha Release From Human Mononuclear Cells - Effects of cAMP and cGMP-Dependent Protein Kinase Inhibitors"
  • 165. Lee S. J., Christenson L., Martin T.Shen S. S., Develop. Biol., 180, 324 - 335 (1996), "The Cyclic GMP-Mediated Calcium Release Pathway in Sea Urchin Eggs is not Required for the Rise in Calcium During Fertilization"
  • 166. Tamir H., Liu K.-P., Adlersberg M., Hsiung S.-C.Gershon M. D., J. Biol. Chem., 271, 6441 - 6450 (1996), "Acidification of Serotonin-containing Secretory Vesicles Induced by a Plasma Membrane Calcium Receptor"
  • 167. Butt E.Walter U., in 'Platelets: A Practical Approach' IRL Press Oxford, 0, 259 - 278 (1996), "Cyclic Nucleotides: Measurement and Function"
  • 168. Bayliss M. A., Pereira L., Games D. E., Brenton A. G., Harris F. M., Newton R. P.Walton T. J., Proc. 2. MS-Pharmaday Siena Italy #C 17-67 - 68, 0, 67 - 68 (1996), "Fast-Atom Bombardment Mass Spectrometry of Site-Specific Effectors of Cyclic Nucleotide Dependent Protein Kinases"
  • 169. Yu S.-M., Cheng Z.-J.Kuo S.-C., Br. J. Pharmacol., 114, 1227 - 1235 (1995), "Antiproliferative Effects of A02011-1, an Adenylate Cyclase Activator, in Cultured Vascular Smooth Muscle Cells of Rat"
  • 170. Gjertsen B. T., Mellgren G., Otten A., Maronde E., Genieser H.-G., Jastorff B., Vintermyr O. K., McKnight G. S.Doeskeland S. O., J. Biol. Chem., 270, 20599 - 20607 (1995), "Novel (Rp)-cAMPS Analogs as Tools for Inhibition of cAMP-Kinase in Cell Culture"
  • 171. Bäumner D.Nawrath H., Eur. J. Pharmacol., 273, 295 - 298 (1995), "Effects of Inhibitors of cGMP-dependent Protein Kinase in Atrial Heart and Aortic Smooth Muscle From Rats"
  • 172. Butt E., Pöhler D., Genieser H.-G., Huggins J. P.Bucher B., Br. J. Pharmacol., 116, 3110 - 3116 (1995), "Inhibition of Cyclic GMP-dependent Protein Kinase-mediated Effects by (Rp)-8-bromo-PET- cyclic GMPS"
  • 173. Genieser H.-G., Proc. 9. Int. Conf. Second Mess. & Phosphoprot. TN USA, 0, 0 - 0 (1995), "Lipophilic Ranking of Biologically Important Cyclic Nucleotides"
  • 174. Rodriguez-Pascual F., Miras-Portugal M. T.Torres M., Neuroscience, 67, 149 - 157 (1995), "Cyclic GMP-dependent Protein Kinase Activation Mediates Inhibition of Catecholamines Secretion and Ca 2+ Influx in Bovine Chromaffin Cells"
  • 175. Harris F. M., Wilkins A. C. R., Bayliss M. A., Brenton A. G., Games D. E., Newton R. P., Langridge J. I.Walton T. J., Intl. Symp. Appl. Mass Spec. Health Sci. Spain, 0, 0 - 0 (1995), "Mass Spectrometric Analysis of Novel Effectors of Cyclic Nucleotide-dependent Protein Kinases"
  • 176. Linden D. J., Dawson T. M.Dawson V. L., J. Neurosci., 15, 5098 - 5105 (1995), "Evaluation of the Nitric Oxide/cGMP-dependent Protein Kinase Cascade in the Induction of Cerebellar Long-Term Depression in Culture"
  • 177. Pöhler D., Butt E., Meißner J., Müller S., Walter U., Lohmann S. M.Jarchau T., FEBS Lett., 374, 419 - 425 (1995), "Expression, Purification, and Characterization of the cGMP-dependent Protein Kinases Iß and II Using the Baculovirus System"
  • 178. Sumii K.Sperelakis N., Circ. Res., 77, 803 - 812 (1995), "cGMP-Dependent Protein Kinase Regulation of the L-Type Ca 2+ Current in Rat Ventricular Myocytes"
  • 179. Surmeier D. J., Bargas J., Hemmings H. C., Nairn A. C.Greengard P., Neuron, 14, 385 - 397 (1995), "Modulation of Calcium Currents by a D1 Dopaminergic Protein Kinase/Phosphatase Cascade in Rat Neostriatal Neurons"
  • 180. Meriney S. D., Gray D. B.Pilar G. R., Nature, 369, 336 - 339 (1994), "Somatostatin-Induced Inhibition of Neuronal Ca 2+ Current Modulated by cGMP-dependent Protein Kinase"
  • 181. Meriney S. D., Gray D. B.Pilar G. R., Nature, 371, 812 - 0 (1994), "Somatostatin-Induced Inhibition of Neuronal Ca 2+ Current Modulated by cGMP-dependent Protein Kinase (Correction)"
  • 182. Ouedraogo S., Stoclet J.-C.Bucher B., Br. J. Pharmacol., 112, 867 - 872 (1994), "Effects of cyclic GMP and Analogues on Neurogenic Transmission in the Rat Tail Artery"
  • 183. Butt E., Eigenthaler M.Genieser H.-G., Eur. J. Pharmacol., 269, 265 - 268 (1994), "(Rp)-8-pCPT-cGMPS, a Novel cGMP-dependent Protein Kinase Inhibitor"
  • 184. Horstrup K., Jablonka B., Hönig-Liedl P., Just M., Kochsiek K.Walter U., Eur. J. Biochem., 225, 21 - 27 (1994), "Phosphorylation of Focal Adhesion Vasodilator-stimulated Phosphoprotein at Ser 157 in Intact Human Platelets Correlates With Fibrinogen Receptor Inhibition"
  • 185. Pinsky D. J., Naka Y., Chowdhury N. C., Liao H., Oz M. C., Michler R. E., Kubaszewski E., Malinski T.Stern D. M., Proc. Natl. Acad. Sci. USA, 91, 12086 - 12090 (1994), "The Nitric Oxide Cyclic GMP Pathway in Organ Transplantation: Critical Role in Successful Lung Preservation"
  • 186. Burkhardt M., Glazova M., Gambaryan S., Vollkommer T., Butt E., Bader B., Heermeier K., Lincoln T. M., Walter U.Palmetshofer A., 12th Protein Kinase Symp. NO/cGMP and Protein Kinase Signaling Bad Brückenau/Germany and J.Biol. Chem. 275 33536 - 33541 ,,'33536, 0, 2000 - 0 (0), "KT5823 Inhibits cGMP-Dependent Protein Kinase Activity in Vitro but not in Intact Human Platelets and Rat Mesangial Cells"
  • 187. Rah S.-Y., Kwak J.-Y.Kim U.-H., Scientific Reports, 0, 0 - 0 (0), "ADP-Ribose/TRM2-mediated Ca2+ Signaling is Essential for Cytolytic Degranulation and Antitumor Activity of Natural Killer Cells"

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