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ddTTP-α-S

2', 3'- Dideoxythymidine- 5'- O- (1- thiotriphosphate), Rp-/Sp-isomers (Rp-/Sp-ddTTP-α-S)
Cat. No.: D 029
    
CAS No.: [154771-48-9]
Shipping: Dry ice
Product Name Price (net) Qty
Cat. No.: D 029-05
Unit: 5 µmol / ~2.4 mg
$313.00

For other salt forms or a guaranteed higher purity please inquire. Useful in mass spectrometric genotyping. Detailed technical information available. Reference: Sauer et al., Nucleic Acids Res., 28 (5), e13 (2000).

 

Vial containing 500 µl of 10 mM aqueous solution of pH 7.6

Cat. No. D 029
CAS number [154771-48-9]
Purity > 95% HPLC for mixture of Rp-/Sp-isomers
Salt form Sodium
Appearance 10 mM aqueous solution of pH 7.6
Storage temperature -70°C / -94°F
Molecular formula C₁₀H₁₇N₂O₁₂P₃S (free acid)
Molecular weight [g/mol] 482.2 (free acid)
Absorption max [nm] 267
Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] 9600
  • 1. Tost J., Schatz P., Schuster M., Berlin K.Gut I. G., Nucleic Acids Res. e50, 31, 0 - 0 (2003), "Analysis and Accurate Quantification of CpG Methylation by MALDI Mass Spectrometry"
  • 2. Tost J., Brandt O., Boussicault F., Derbala D., Caloustian C., Lechner D.Gut I. G., Nucleic Acids Res. e96, 30, 0 - 0 (2002), "Molecular Haplotyping at High Throughput"
  • 3. Sauer S., Gelfand D. H., Boussicault F., Bauer K., Reichert F.Gut I. G., Nucleic Acids Res. e22, 30, 0 - 0 (2002), "Facile Method for Automated Genotyping of Single Nucleotide Polymorphisms by Mass Spectrometry"
  • 4. Sauer S.Gut I. G., J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci., 782, 73 - 87 (2002), "Genotyping Single-Nucleotide Polymorphisms by Matrix-Assisted Laser-Desorption/Ionization Time-of-Flight Mass Spectrometry"
  • 5. Lechner D., Lathrop G. M.Gut I. G., Curr. Opin. Chem. Biol., 6, 31 - 38 (2002), "Large-Scale Genotyping by Mass Spectrometry : Experience, Advances and Obstacles"
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  • 7. Sauer S., Lechner D., Berlin K., Plancon C., Heuermann A., Lehrach H.Gut I. G., Nucleic Acids Res. 100e, 28, 0 - 0 (2000), "Full Flexibility Genotyping of Single Nucleotide Polymorphisms by the GOOD Assay"
  • 8. Sauer S., Lechner D., Berlin K., Lehrach H., Escary J.-L., Fox N.Gut I. G., Nucleic Acids Res. e13, 28, 0 - 0 (2000), "A Novel Procedure for Efficient Genotyping of Single Nucleotide Polymorphisms"
  • 9. Ryder S. P.Strobel S. A., Methods Enzymol., 18, 38 - 50 (1999), "Nucleotide Analog Interference Mapping"
  • 10. Gut I. G.Beck S., in Griffin, A.M.; Griffin, H.G. (ed.): Molecular Biology: Current Innovations and Future Trends - Part 1, Horizon Scientific Press, Wymondham, UK, 0, 147 - 157 (1995), "Mass Spectrometry in Molecular Biology"