For other salt forms or a guaranteed higher purity please inquire. Analogue useful for ATP receptor mapping. Competes with ATP and thus could be the reason for purine riboside toxicity. Detailed technical information available. Reference: Kozlowska et al., Toxicol. Lett., 104, 171 - 181 (1999).
Vial containing 500 µl of 10 mM aqueous solution of pH 7.6
| Cat. No. | P 009 |
| CAS number | [23197-96-8] |
| Purity | > 95% HPLC |
| Salt form | Sodium |
| Appearance | 10 mM aqueous solution of pH 7.6 |
| Storage temperature | -70°C / -94°F |
| Molecular formula | C₁₀H₁₅N₄O₁₃P₃ (free acid) |
| Molecular weight [g/mol] | 492.2 (free acid) |
| Absorption max [nm] | 263 |
| Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] | 8000 |
- 1. Kozlowska M., Smolenski R. T., Makarewicz W., Hoffmann C., Jastorff B.Swierczynski J., Toxicol. Lett., 104, 171 - 181 (1999), "ATP Depletion, Purine Riboside Triphosphate Accumulation and Rat Thymocyte Death Induced by Purine Riboside"
- 2. Ortoleva-Donnelly L., Kronman M.Strobel S. A., Biochemistry, 37, 12933 - 12942 (1998), "Identifying RNA Minor Groove Tertiary Contacts by Nucleotide Analogue Interference Mapping with N#-Methylguanosine"
- 3. Erneux C.Miot F., Methods Enzymol., 159, 520 - 530 (1988), "Cyclic Nucleotide Analogs Used to Study Phosphodiesterase Catalytic and Allosteric Sites"
- 4. Kwiatkowski A. P.King M. M., Biochemistry, 26, 7636 - 7640 (1987), "Mapping of the Adenosine 5'-Triphosphate Binding Site of Type II Calmodulin-Dependent Protein Kinase"
- 5. Erneux C., Couchie D., Dumont J. E., Baraniak J., Stec W. J., Garcia Abbad E., Petridis G.Jastorff B., Eur. J. Biochem., 115, 503 - 510 (1981), "Specificity of cyclic GMP Activation of a Multi-substrate Cyclic Nucleotide Phosphodiesterase from Rat Liver"
