Hydrolytically stable analogue of GDP and starting structure for synthesis of α/β hydrolysis-resistant tri- and polyphosphates. Detailed technical information available. References: Sandoval et al., Proc. Nat. Acad. Sci. USA, 75, 3178 - 3182 (1978); Vulevic et al., Biochemistry, 36, 12828 - 12835 (1997); Byron, Chemtracts, 11, 980 - 984 (1998).
Vial containing 500 µl of 10 mM aqueous solution of pH 7.6
| Cat. No. | G 024 |
| CAS number | [32381-15-0] |
| Purity | > 95% HPLC |
| Salt form | Sodium |
| Appearance | 10 mM aqueous solution of pH 7.6 |
| Storage temperature | -20°C / -4°F |
| Molecular formula | C₁₁H₁₇N₅O₁₀P₂ (free acid) |
| Molecular weight [g/mol] | 441.2 (free acid) |
| Absorption max [nm] | 252 |
| Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] | 13500 |
- 1. Vulevic B., Lobert S.Correia J. J., Biochemistry, 36, 12828 - 12835 (1997), "Role of Guanine Nucleotides in the Vinblastine-Induced Self-Association of Tubulin: Effects of Guanosine Alpha, Beta-Methylenetriphosphate and Guanosine Alpha, Beta-Methylenediphosphate"
- 2. Sandoval I. V., Jameson J. L., Niedel J., MacDonald E.Cuatrecasas P., Proc. Natl. Acad. Sci. USA, 75, 3178 - 3182 (1978), "Role of Nucleotides in Tubulin Polymerization: Effect of Guanosine 5'-Methylene Diphosphonate"
