Basket (0 Items) - Amount: 0.00$2'- O- Methylguanosine- 3', 5'- cyclic monophosphate ( 2'-O-Me-cGMP )
Epac-negative control
Cat. No.: M 036 CAS No.: [[949909-73-3]]
C11H13N5O7P•Na; MW 381.2; λmax 252 nm; ε 13500; sodium salt; purity > 98% HPLC. For other salt forms please inquire. Relatively polar analogue of cyclic GMP which activate neither protein kinase G nor Epac. 2'-O-Me-cGMP can be used as an inactive control in patch clamp applications. Also suitable for receptor mapping studies. The structurally related cAMP-based analogue 2'-O-Me-cAMP is offered as well (Cat. No. M 050). Detailed technical information available. Reference: Strassmaier & Karpen, J. Med. Chem., 50, 4186 - 4194 (2007); Matthiesen & Nielsen, Biochem. J., 423, 401 - 409 (2009); Jäger et al., Br. J. Pharmacol., 161, 1645 - 1660 (2010).
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