C₁₀H₁₀BrN₅O₇P•Na; MW 446.1; λ_max 260 nm; ε 15000; sodium salt, purity > 99% HPLC. Specially purified, typical fluorescent impurities removed. For other salt forms or metabolites of 8-Br-cGMP please inquire. Activator of cGMP-dependent protein kinases I α, I ß & type II and cGMP-gated ion channels (cyclic GMP agonist). Increased metabolical stability compared to cGMP, but not completely stable as often stated. 8-pCPT-cGMP (Cat. No. C 009), a highly membrane-permeant and metabolically resistant cGMP-agonist seems to be superior for most applications. Detailed technical information and reference list available. Reference: Rapoport et al., Proc. Natl. Acad. Sci. USA, 79, 6470 - 6474 (1982). 8-Br-cGMP is also available in an inexpensive normal quality form ( B 004 Economy Grade ).