Basket (0 Items) - Amount: 0.00$8- [ Pharos-575]- adenosine- 3', 5'- cyclic monophosphate ( 8-[φ-575]-cAMP )
Membrane-permeant, fluorescent analogue of cyclic AMP
Cat. No.: P 019 CAS No.: [pending]
Sodium salt; purity > 98% HPLC. For other salt forms please inquire.
cyclic AMP connected to the relatively small Pharos 575 dye (λexc 577 nm, λem 605 nm) by a spacer. The fluorophore can be excited e.g. by a Kr/Ar laser. Due to its high lipophilicity and bright red fluorescence 8-[φ-575]-cAMP is especially suitable for studies with intact cells. Upon binding to PKA a small hypsochromic shift is observed. Detailed technical information available. Reference: Moll et al., BMC Biochem., 9: 18 (2008).
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