8- Piperidinoadenosine- 3', 5'- cyclic monophosphorothioate, Rp- isomer ( Rp-8-PIP-cAMPS )
C15H20N6O5PS•Na; MW 450.4; λmax 273 nm; ε 15000; sodium salt; purity > 99% HPLC, specially purified. For other salt forms please inquire. Lipophilic site-selective analogue of the protein kinase A inhibitor Rp-cAMPS (Cat. No. A 002) with extremely high preference for site B of cAK type II. Resistant against mammalian cyclic nucleotide-dependent phosphodiesterases. Significantly more lipophilic and membrane-permeant compared to Rp-cAMPS. Detailed technical information and updated reference list available on request. Reference: Øgreid et al., Eur. J. Biochem., 221, 1089 - 1094 (1994).
Protected under patent DE 3802865.4 exclusively licensed to BIOLOG LSI
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