Basket (0 Items) - Amount: 0.00$β- Phenyl- 1, N²- ethenoguanosine- 3', 5'- cyclic monophosphate ( PET-cGMP )
Site-selective analogue of cyclic GMP
Cat. No.: P 001 CAS No.: [78080-27-0] Bulk available
C18H15N5O7P•Na; MW 467.3; λmax 252 nm; ε 37400; sodium salt, purity > 98% HPLC. For other salt forms or metabolites please inquire. Potent membrane-permeant activator of both isozymes I α and I ß of cGMP-dependent protein kinase while only a poor stimulator of type II. Common agonists such as 8-Br-cGMP or 8-pCPT-cGMP mainly activate kinase subtypes I α and II. Detailed technical information and updated reference list available. References: Gamm et al., J. Biol. Chem., 270, 27380 - 27388 (1996), Vaandrager et al., J. Biol. Chem., 272, 11816 - 11823 (1997).
| << Back | Basket (0 Items) >> |