8- Nitroguanosine- 3', 5'- cyclic monophosphate ( 8-NO2-cGMP )

Second messenger of NO
Cat. No.: N 011   CAS No.: [pending]   
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C10H10N6O9P•Na; MW 412.2. The nitrated derivative of cGMP, 8-NO2-cGMP (8-Nitro-cGMP), is considered to play an important role in NO-mediated signal transduction. Formation of protein Cys-cGMP adducts by 8-NO2-cGMP was identified as a new post-translational modification of proteins, which is called S-guanylation. Reference: Sawa et al., Nat. Chem. Biol., 3, 727 - 735 (2007).

 



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