N6- Mono- tert. butylcarbamoyladenosine- 3', 5'- cyclic monophosphate ( 6-MBC-cAMP )

Membrane-permeant, site-selective PKA agonist
Cat. No.: M 012   CAS No.: [84433-46-5]   
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C15H20N6O7P•Na; MW 450.3; λmax 268 nm; ε 23700; sodium salt; purity > 98% HPLC. For other salt forms please inquire. Site selective activator of protein kinase A ( cyclic AMP agonist ) strongly preferring the A site of cAK II. Together with e.g. Sp-5,6-DCl-cBIMPS (Cat. No. D 014) selective stimulation of type II can be achieved. 6-MBC-cAMP is considered not to activate Epac. Detailed technical information and updated reference list available on request. References: Maronde et al., J. Pineal Res., 27, 170 - 182 (1999); Fricke et al., Endocrinology, 145, 4940 - 4947 (2004).

 



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